[Immune-complex mechanisms of the pathogenesis of systemic lupus erythematosus].
1986
D V Preobrazhenskiĭ, and
S P Builov
UI
MeSH Term
Description
Entries
D008180
Lupus Erythematosus, Systemic
A chronic, relapsing, inflammatory, and often febrile multisystemic disorder of connective tissue, characterized principally by involvement of the skin, joints, kidneys, and serosal membranes. It is of unknown etiology, but is thought to represent a failure of the regulatory mechanisms of the autoimmune system. The disease is marked by a wide range of system dysfunctions, an elevated erythrocyte sedimentation rate, and the formation of LE cells in the blood or bone marrow.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000936
Antigen-Antibody Complex
The complex formed by the binding of antigen and antibody molecules. The deposition of large antigen-antibody complexes leading to tissue damage causes IMMUNE COMPLEX DISEASES.