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A previous study of the MOD-MEM test showed promising results. We have attempted to repeat the study using a blind coded series of 210 blood samples from normal subjects and patients with either benign or malignant disease. Using standard criteria the false negative rate for cancer patients averaged 43% and the false positive rate for non-cancer patients averaged 34%. The results indicate that the test at the present time, under routine laboratory conditions, is not reliably reproducible and does not have the ability to effectively discriminate between benign and malignant disease. It is suggested that blind coded studies be used more frequently in assessment of tests with cancer detection potential.
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
March 1976,
Archiv fur Gynakologie,
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
June 1975,
Journal of immunological methods,
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
July 1976,
Journal of clinical pathology,
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
August 1973,
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J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
December 1974,
Clinical and experimental immunology,
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
August 1976,
The British journal of ophthalmology,
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
January 1979,
Zhonghua zhong liu za zhi [Chinese journal of oncology],
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
January 1979,
Cellular and molecular biology, including cyto-enzymology,
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
December 1976,
British journal of cancer,
J A Pritchard, and
W H Sutherland, and
C Teasdale, and
R H Whitehead, and
T J Deeley, and
L E Hughes
October 1985,
Journal of immunological methods,
