-transparent.png){kind=logo}
Asymmetric epoxidation of a series of olefinic substrates with sodium percarbonate oxidant in the presence of homogeneous catalysts based on Mn complexes with bis-amino-bis-pyridine ligands is reported. Sodium percarbonate is a readily available and environmentally benign oxidant that is studied in these reactions for the first time. The epoxidation proceeded with good to high yields (up to 100%) and high enantioselectivities (up to 99% ee) using as low as 0.2 mol. % catalyst loadings. The epoxidation protocol is suitable for various types of substrates, including unfunctionalized alkenes, α,β-unsaturated ketones, esters (cis- and trans-), and amides (cis- and trans-). The reaction mechanism is discussed.
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
August 2009,
Organic letters,
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
February 2016,
Organic letters,
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
May 2009,
The Journal of organic chemistry,
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
December 1997,
Inorganic chemistry,
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
July 2014,
The Journal of organic chemistry,
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
January 2007,
Angewandte Chemie (International ed. in English),
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
August 2013,
Organic letters,
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
November 2020,
Chemical communications (Cambridge, England),
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
September 2008,
Chemical reviews,
Varvara A Drozd, and
Roman V Ottenbacher, and
Konstantin P Bryliakov
August 2012,
Angewandte Chemie (International ed. in English),
