BIOMAT Database Logo BIOMAT Database Logo

Nephrotoxic effect of cyclosporine A can be reversed by dopamine. 1987

T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff

UI MeSH Term Description Entries
D007610 Kallikreins Proteolytic enzymes from the serine endopeptidase family found in normal blood and urine. Specifically, Kallikreins are potent vasodilators and hypotensives and increase vascular permeability and affect smooth muscle. They act as infertility agents in men. Three forms are recognized, PLASMA KALLIKREIN (EC 3.4.21.34), TISSUE KALLIKREIN (EC 3.4.21.35), and PROSTATE-SPECIFIC ANTIGEN (EC 3.4.21.77). Kallikrein,Kininogenase,Callicrein,Dilminal,Kallidinogenase,Kalliginogenase,Kallikrein A,Kallikrein B',Kallikrein Light Chain,Kinin-Forming Enzyme,Padutin,alpha-Kallikrein,beta-Kallikrein,beta-Kallikrein B,Enzyme, Kinin-Forming,Kinin Forming Enzyme,Light Chain, Kallikrein,alpha Kallikrein,beta Kallikrein,beta Kallikrein B
D007668 Kidney Body organ that filters blood for the secretion of URINE and that regulates ion concentrations. Kidneys
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D011453 Prostaglandins A group of compounds derived from unsaturated 20-carbon fatty acids, primarily arachidonic acid, via the cyclooxygenase pathway. They are extremely potent mediators of a diverse group of physiological processes. Prostaglandin,Prostanoid,Prostanoids
D012083 Renin A highly specific (Leu-Leu) endopeptidase that generates ANGIOTENSIN I from its precursor ANGIOTENSINOGEN, leading to a cascade of reactions which elevate BLOOD PRESSURE and increase sodium retention by the kidney in the RENIN-ANGIOTENSIN SYSTEM. The enzyme was formerly listed as EC 3.4.99.19. Angiotensin-Forming Enzyme,Angiotensinogenase,Big Renin,Cryorenin,Inactive Renin,Pre-Prorenin,Preprorenin,Prorenin,Angiotensin Forming Enzyme,Pre Prorenin,Renin, Big,Renin, Inactive
D003524 Cyclosporins A group of closely related cyclic undecapeptides from the fungi Trichoderma polysporum and Cylindocarpon lucidum. They have some antineoplastic and antifungal action and significant immunosuppressive effects. Cyclosporins have been proposed as adjuvants in tissue and organ transplantation to suppress graft rejection. Cyclosporines
D004298 Dopamine One of the catecholamine NEUROTRANSMITTERS in the brain. It is derived from TYROSINE and is the precursor to NOREPINEPHRINE and EPINEPHRINE. Dopamine is a major transmitter in the extrapyramidal system of the brain, and important in regulating movement. A family of receptors (RECEPTORS, DOPAMINE) mediate its action. Hydroxytyramine,3,4-Dihydroxyphenethylamine,4-(2-Aminoethyl)-1,2-benzenediol,Dopamine Hydrochloride,Intropin,3,4 Dihydroxyphenethylamine,Hydrochloride, Dopamine
D005260 Female Females
D006439 Hemodynamics The movement and the forces involved in the movement of the blood through the CARDIOVASCULAR SYSTEM. Hemodynamic

Related Publications

T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Hydroxylated, Hydroxymethylated, Dihydroxylated, and Trihydroxylated Cyclosporine Metabolites Can Be Nephrotoxic in Kidney Transplant Recipients.
June 2016, Transplantation proceedings,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
In vivo fluorescence microscopy reveals cyclosporine G to be less nephrotoxic than cyclosporine A.
April 1988, Transplantation proceedings,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Acute cyclosporine renal dysfunction reversed by dopamine infusion in healthy subjects.
December 1989, Kidney international,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Aging by telomere loss can be reversed.
January 2011, Cell stem cell,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Can glomerulosclerosis be reversed?
June 2006, Nature clinical practice. Nephrology,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Nephrotoxic aspects of cyclosporine.
March 2004, Transplantation proceedings,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Nitratase adaptation; an apparent effect of penicillin which can be reversed by salt.
August 1949, British journal of experimental pathology,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Can insulin resistance be reversed by insulin therapy?
January 2009, Medical hypotheses,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Can luteal regression be reversed?
October 2006, Reproductive biology and endocrinology : RB&E,
T L Kho, and J Teule, and K M Leunissen, and G A Heidendal, and P J Lijnen, and A K Amery, and J P van Hooff
Can renal fibrosis be reversed?
October 2005, Pediatric nephrology (Berlin, Germany),
Copied contents to your clipboard!