Biomaterial Database

Two new iridoid glycosides from Hedyotis diffusa. 2023

Juan Wu, and Zhu-Jun Ye, and Li-Juan Yu, and Xuan-Qin Chen

Faculty of Life Science and Technology, Kunming University of Science and Technology, Kunming 650500, China.

Two new iridoid glycosides, named productasperulosidic acid butyl ester (1) and E-6-O-3-hydroxy-p-methoxycinnamoyl scandoside methyl ester (2), along with nine known ones (3-11), were isolated from Hedyotis diffusa Willd. The structures of them were elucidated by extensive 1D, 2D NMR and HR-ESI-MS spectral data. Compounds 1-11 showed no significant cytotoxic activity against HeLa cells.

UI	MeSH Term	Description	Entries
D004365	Drugs, Chinese Herbal	Chinese herbal or plant extracts which are used as drugs to treat diseases or promote general well-being. The concept does not include synthesized compounds manufactured in China.	Chinese Herbal Drugs,Plant Extracts, Chinese,Chinese Drugs, Plant,Chinese Plant Extracts,Extracts, Chinese Plant,Herbal Drugs, Chinese
D006367	HeLa Cells	The first continuously cultured human malignant CELL LINE, derived from the cervical carcinoma of Henrietta Lacks. These cells are used for, among other things, VIRUS CULTIVATION and PRECLINICAL DRUG EVALUATION assays.	Cell, HeLa,Cells, HeLa,HeLa Cell
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015394	Molecular Structure	The location of the atoms, groups or ions relative to one another in a molecule, as well as the number, type and location of covalent bonds.	Structure, Molecular,Molecular Structures,Structures, Molecular
D057889	Iridoid Glycosides	A subclass of iridoid compounds that include a glycoside moiety, usually found at the C-1 position.	Iridoidglycosides,Secoiridoid Glycosides,Glycosides, Iridoid,Glycosides, Secoiridoid
D032064	Hedyotis	A plant genus of the family RUBIACEAE. Members contain anthraquinones and iridoids. H. diffusa is used in DRUGS, CHINESE HERBAL.	Hedyoti