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Ductular reaction develops during liver regeneration, fibrosis, and carcinogenesis. However, the types, stages of formation, and topography of ductular profiles in various pathologies remain insufficiently studied. Using the model of common bile duct occlusion, we showed that the number and topography of ductular profiles are closely related to the duration of biliary obstruction. The ductular profiles can be located inside the portal tract, along the existing bile ducts, and/or intramurally, around the portal vein, periportally, inside the lobules, in the portocaval fibrous connections, in the adventitia of the hepatic veins, in the septs connecting the portal tracts, and also in the "portal plate" of the liver. The ductular profiles can be formed as a result of expansion of existing bile ducts, cholangiocyte proliferation, as well as transdifferentiation of hepatocytes and activation of mesenchymal stem cells.
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
April 1962,
Experimental and molecular pathology,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
August 1962,
Experimental and molecular pathology,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
July 1985,
The American journal of pathology,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
July 1959,
American journal of clinical pathology,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
May 2023,
FEBS open bio,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
September 2020,
Scientific reports,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
July 1974,
Biulleten' eksperimental'noi biologii i meditsiny,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
January 1990,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
January 1991,
Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas,
I S Bebiashvili, and
M Sh Kakabadze, and
S M Gvidiani, and
K B Tsomaia, and
S A Gusev, and
D J Kordzaia
January 1975,
Bulletin of experimental biology and medicine,
