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Optical flexible biosensors: From detection principles to biomedical applications. 2022

Wanxia Wu, and Lan Wang, and Ya Yang, and Wei Du, and Wenhui Ji, and Zhijie Fang, and Xiyan Hou, and Qiong Wu, and Chengwu Zhang, and Lin Li
Key Laboratory of Flexible Electronics (KLOFE) & Institute of Advanced Materials (IAM), Nanjing Tech University (NanjingTech), Nanjing, 211800, China.

Optical flexible biosensors are novel sensors fabricated on flexible or ductile materials that are used for the detection of analytes. Compared to traditional sensors, these biosensors offer greater flexibility, which allows them to adapt to different working environments, to meet the deformation requirements of humans. Flexible devices can not only detect alterations in analytes in vitro, but can also realize real-time and non-invasive monitoring of the variation of physical conditions or metabolites in vivo. Flexible devices are earning increasing attention from researchers and clinicians. In the present review, we summarize and introduce the detection principles, key analytes, and applications of optical flexible biosensors in the diagnosis/treatment of diseases as well as health detection. Moreover, the remaining challenges of flexible devices and their perspectives have also been addressed. We hope that this review will pave ways for the development of more feasible and multifunctional flexible devices.

UI MeSH Term Description Entries
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000076251 Wearable Electronic Devices Electronic implements worn on the body as an implant or as an accessory. Examples include wearable diagnostic devices, wearable ACTIVITY TRACKERS, wearable INFUSION PUMPS, wearable computing devices, SENSORY AIDS, and electronic pest repellents. Wearable Computer,Electronic Skin,Wearable Devices,Wearable Technology,Computer, Wearable,Device, Wearable,Device, Wearable Electronic,Electronic Device, Wearable,Skin, Electronic,Technology, Wearable,Wearable Computers,Wearable Device,Wearable Electronic Device,Wearable Technologies
D015374 Biosensing Techniques Any of a variety of procedures which use biomolecular probes to measure the presence or concentration of biological molecules, biological structures, microorganisms, etc., by translating a biochemical interaction at the probe surface into a quantifiable physical signal. Bioprobes,Biosensors,Electrodes, Enzyme,Biosensing Technics,Bioprobe,Biosensing Technic,Biosensing Technique,Biosensor,Electrode, Enzyme,Enzyme Electrode,Enzyme Electrodes,Technic, Biosensing,Technics, Biosensing,Technique, Biosensing,Techniques, Biosensing

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