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A mild and efficient method for the synthesis of pyrroles using MIL-53(Al) as a catalyst under solvent-free sonication. 2019

Hai Truong Nguyen, and Linh Ho Thuy Nguyen, and Tan Le Hoang Doan, and Phuong Hoang Tran
Faculty of Chemistry, University of Science, Vietnam National University - Ho Chi Minh City 721337 Vietnam thphuong@hcmus.edu.vn.

A highly efficient method for the synthesis of pyrroles using MIL-53(Al) as a catalyst has been developed under solvent-free sonication. This reaction has a broad substrate scope and high yields were obtained within a short reaction time. Remarkably, no additional additives and volatile organic solvent are required for this method and the MIL-53(Al) could be recovered and reused several times without significant drop-off in catalytic activity.

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