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Mild hypnotics are often recommended for young children with sleep problems. This study assesses the efficacy of trimeprazine tartrate in 1 to 3 year old children with persistent and severe night waking in a double blind crossover trial with placebo. Children on treatment with trimeprazine had significantly fewer wakings, less time awake at night, and more night time sleep compared with those on treatment with placebo. There were no differences in these sleep variables when the first and last (fourth) week of treatment with drugs were compared. Follow up observations showed no significant difference in any sleep variables from baseline measures. The results are consistent with the idea that trimeprazine tartrate may be a useful short term treatment for night waking in young children.
E A Simonoff, and
G Stores
April 1959,
Lancet (London, England),
E A Simonoff, and
G Stores
August 1981,
British journal of anaesthesia,
E A Simonoff, and
G Stores
January 1960,
The Medical journal of Australia,
E A Simonoff, and
G Stores
October 1961,
Anaesthesia,
E A Simonoff, and
G Stores
January 1960,
Journal of the Royal Army Medical Corps,
E A Simonoff, and
G Stores
May 1970,
British medical journal,
E A Simonoff, and
G Stores
January 1997,
Acta microbiologica et immunologica Hungarica,
E A Simonoff, and
G Stores
November 1989,
Archives of disease in childhood,
E A Simonoff, and
G Stores
February 1970,
British journal of preventive & social medicine,
