Biomaterial Database

Visual and Refractive Outcomes Following Laser Blended Vision With Non-linear Aspheric Micro-anisometropia (PRESBYOND) in Myopic and Hyperopic Patients. 2022

Andrea Russo, and Dan Z Reinstein, and Ottavia Filini, and Timothy J Archer, and Alessandro Boldini, and Gloria Cardin, and Giulia Festa, and Francesco Morescalchi, and Chiara Salvalai, and Francesco Semeraro

OBJECTIVE To report 6-month visual and refractive outcomes following PRESBYOND Laser Blended Vision (Carl Zeiss Meditec) treatment using non-linear aspheric micro-anisometropia laser in situ keratomileusis (LASIK) for the correction of myopic and hyperopic presbyopia. METHODS A retrospective, non-comparative study of 139 consecutive patients with a mean age of 53.13 ± 5.84 years (range: 42 to 70 years) treated with LASIK-induced micro-anisometropia using the MEL 90 excimer laser and VisuMax femtosecond laser (both Carl Zeiss Meditec). The target refraction was plano for distance eyes (dominant eye) and between -0.50 and -1.50 diopters (D) for near eyes. Patients were observed for 6 months. RESULTS A total of 278 eyes (78 myopic and 200 hyperopic) from 139 patients completed the study. Mean preoperative spherical equivalent (SE) was -3.40 ± 1.83 D (range: -0.50 to -8.25 D) for myopic eyes and +1.61 ± 0.98 D (range: -1.25 to +4.63 D) for hyperopic eyes. Mean postoperative SE refraction of distance eyes was +0.20 ± 0.35 D (range: -0.38 to +1.00 D) and -0.14 ± 0.42 D (range: -1.38 to +0.88 D) for myopic and hyperopic eyes, respectively. Mean postoperative SE refraction of near eyes was -0.90 ± 0.44 D (range: -0.13 to -2.25 D) and -1.21 ± 0.48 D (range: -0.13 to -2.25 D) for myopic and hyperopic eyes, respectively. Mean binocular uncorrected near visual acuity was 0.70 ± 0.28 logMAR (range: 0.32 to 1.00 logMAR) and 0.79 ± 0.27 logMAR (range: 0.25 to 1.00 logMAR) for myopic and hyperopic eyes, respectively. Mean binocular uncorrected distance visual acuity was 1.19 ± 0.18 logMAR (range: 0.63 to 1.25 logMAR) and 1.14 ± 0.26 logMAR (range: 0.40 to 1.25 logMAR) for myopic and hyperopic eyes, respectively. Stereoacuity was better than 100 seconds of arc in 79% of myopic eyes and 85% of hyperopic eyes and all vision quality scores were greater than 90 of 100. No eyes lost two or more lines. CONCLUSIONS The non-linear aspheric micro-anisometropia protocol resulted in safe and effective visual outcomes in patients with both myopic and hyperopic presbyopia. [.

UI	MeSH Term	Description	Entries
D006956	Hyperopia	A refractive error in which rays of light entering the eye parallel to the optic axis are brought to a focus behind the retina, as a result of the eyeball being too short from front to back. It is also called farsightedness because the near point is more distant than it is in emmetropia with an equal amplitude of accommodation. (Dorland, 27th ed)	Farsightedness,Hypermetropia
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009216	Myopia	A refractive error in which rays of light entering the EYE parallel to the optic axis are brought to a focus in front of the RETINA when accommodation (ACCOMMODATION, OCULAR) is relaxed. This results from an overly curved CORNEA or from the eyeball being too long from front to back. It is also called nearsightedness.	Nearsightedness,Myopias,Nearsightednesses
D011305	Presbyopia	The normal decreasing elasticity of the crystalline lens that leads to loss of accommodation.	Presbyopias
D012029	Refraction, Ocular	Refraction of LIGHT effected by the media of the EYE.	Ocular Refraction,Ocular Refractions,Refractions, Ocular
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012189	Retrospective Studies	Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons.	Retrospective Study,Studies, Retrospective,Study, Retrospective
D015858	Anisometropia	A condition of an inequality of refractive power of the two eyes.
D016896	Treatment Outcome	Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series.	Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D054018	Lasers, Excimer	Gas lasers with excited dimers (i.e., excimers) as the active medium. The most commonly used are rare gas monohalides (e.g., argon fluoride, xenon chloride). Their principal emission wavelengths are in the ultraviolet range and depend on the monohalide used (e.g., 193 nm for ArF, 308 nm for Xe Cl). These lasers are operated in pulsed and Q-switched modes and used in photoablative decomposition involving actual removal of tissue. (UMDNS, 2005)	Argon Fluoride Excimer Lasers,Excimer Lasers,Krypton Chloride Excimer Lasers,Xenon Chloride Excimer Lasers,ArF Excimer Lasers,ArF Lasers,Argon Fluoride Lasers,Excimer Laser,Excimer Lasers, ArF,Excimer Lasers, Argon Fluoride,Excimer Lasers, KrCl,Excimer Lasers, Krypton Chloride,Excimer Lasers, XeCl,Excimer Lasers, Xenon Chloride,KrCl Excimer Lasers,Krypton Chloride Lasers,Lasers, ArF Excimer,Lasers, Argon Fluoride Excimer,Lasers, KrCl,Lasers, Krypton Chloride,Lasers, Krypton Chloride Excimer,Lasers, XeCl Excimer,Lasers, Xenon Chloride,Lasers, Xenon Chloride Excimer,XeCl Lasers,Xenon Chloride Lasers,ArF Excimer Laser,ArF Laser,Argon Fluoride Laser,Chloride Laser, Krypton,Chloride Laser, Xenon,Chloride Lasers, Krypton,Chloride Lasers, Xenon,Excimer Laser, ArF,Excimer Laser, KrCl,Excimer Laser, XeCl,Fluoride Laser, Argon,Fluoride Lasers, Argon,KrCl Excimer Laser,KrCl Laser,KrCl Lasers,Krypton Chloride Laser,Laser, ArF,Laser, ArF Excimer,Laser, Argon Fluoride,Laser, Excimer,Laser, KrCl,Laser, KrCl Excimer,Laser, Krypton Chloride,Laser, XeCl,Laser, XeCl Excimer,Laser, Xenon Chloride,Lasers, ArF,Lasers, Argon Fluoride,Lasers, KrCl Excimer,Lasers, XeCl,XeCl Excimer Laser,XeCl Excimer Lasers,XeCl Laser,Xenon Chloride Laser