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Upadacitinib in refractory ulcerative colitis. 2022

Gabriel Rodríguez Toboso, and Pedro Ángel Rivera Vaquerizo, and María Nieves Martínez López, and María Del Mar Blasco Colmenarejo, and Félix Calvo Hernán, and Jose María Moreno Planas
Aparato Digestivo , Hospital General Universitario de Albacete, España .

We report the first clinical-practice case to date of treatment with upadacitinib for ulcerative colitis, prior refractoriness to all therapeutic options, and preventing proctocolectomy as of today after treatment for 14 months.

UI MeSH Term Description Entries
D003093 Colitis, Ulcerative Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN. Colitis Gravis,Idiopathic Proctocolitis,Inflammatory Bowel Disease, Ulcerative Colitis Type,Ulcerative Colitis
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D016737 Proctocolectomy, Restorative A surgical procedure involving the excision of the COLON and RECTUM and the formation of an ILEOANAL RESERVOIR (pouch). In patients with intestinal diseases, such as ulcerative colitis, this procedure avoids the need for an OSTOMY by allowing for transanal defecation. Coloproctectomy, Restorative,Ileal Pouch Anal Anastomosis,Proctocolectomy,Total Proctocolectomy,Total Proctocolectomy with Ileal Pouch Anal Anastomosis,Proctocolectomies,Proctocolectomy, Total,Restorative Coloproctectomies,Restorative Coloproctectomy,Restorative Proctocolectomies,Restorative Proctocolectomy,Total Proctocolectomies

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