J García-García, and
I Díaz-Maroto, and
E González-Villar, and
A Martínez-Martín
Complejo Hospitalario Universitario de Albacete, Albacete, España.
UI
MeSH Term
Description
Entries
D009157
Myasthenia Gravis
A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D061067
Antibodies, Monoclonal, Humanized
Antibodies from non-human species whose protein sequences have been modified to make them nearly identical with human antibodies. If the constant region and part of the variable region are replaced, they are called humanized. If only the constant region is modified they are called chimeric. INN names for humanized antibodies end in -zumab.
Antibodies, Humanized,Humanized Antibodies
Related Publications
J García-García, and
I Díaz-Maroto, and
E González-Villar, and
A Martínez-Martín