BIOMAT Database Logo BIOMAT Database Logo

Bacterial Meningitis in Children With Sickle Cell Disease in Angola. 2022

Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
From the Pediatrics, University of Helsinki and Helsinki University Hospital.

Sickle cell disease (SCD) was found in 10% of children with bacterial meningitis (BM) in Luanda, 5-fold more than in the general population. BM children with SCD versus BM children without SCD had higher inflammatory markers, more often had pneumococcal meningitis (71% vs. 39%), and either died (39% vs. 22%) or had a longer hospital stay (15 vs. 11 days).

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D008586 Meningitis, Pneumococcal An acute purulent infection of the meninges and subarachnoid space caused by Streptococcus pneumoniae, most prevalent in children and adults over the age of 60. This illness may be associated with OTITIS MEDIA; MASTOIDITIS; SINUSITIS; RESPIRATORY TRACT INFECTIONS; sickle cell disease (ANEMIA, SICKLE CELL); skull fractures; and other disorders. Clinical manifestations include FEVER; HEADACHE; neck stiffness; and somnolence followed by SEIZURES; focal neurologic deficits (notably DEAFNESS); and COMA. (From Miller et al., Merritt's Textbook of Neurology, 9th ed, p111) Meningitis, Streptococcus pneumoniae,Experimental Pneumococcal Meningitis,Meningitis, Pneumococcal, Experimental,Meningitis, Pneumococcal, Penicillin-Resistant,Meningitis, Pneumococcal, Recurrent,Experimental Pneumococcal Meningitides,Meningitides, Streptococcus pneumoniae,Meningitis, Experimental Pneumococcal,Pneumococcal Meningitides,Pneumococcal Meningitides, Experimental,Pneumococcal Meningitis,Pneumococcal Meningitis, Experimental,Streptococcus pneumoniae Meningitides,Streptococcus pneumoniae Meningitis
D002648 Child A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL. Children
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000755 Anemia, Sickle Cell A disease characterized by chronic hemolytic anemia, episodic painful crises, and pathologic involvement of many organs. It is the clinical expression of homozygosity for hemoglobin S. Hemoglobin S Disease,HbS Disease,Sickle Cell Anemia,Sickle Cell Disease,Sickle Cell Disorders,Sickling Disorder Due to Hemoglobin S,Anemias, Sickle Cell,Cell Disease, Sickle,Cell Diseases, Sickle,Cell Disorder, Sickle,Cell Disorders, Sickle,Disease, Hemoglobin S,Hemoglobin S Diseases,Sickle Cell Anemias,Sickle Cell Diseases,Sickle Cell Disorder
D000810 Angola A republic in southern Africa, southwest of DEMOCRATIC REPUBLIC OF THE CONGO and west of ZAMBIA. Its capital is Luanda.
D016920 Meningitis, Bacterial Bacterial infections of the leptomeninges and subarachnoid space, frequently involving the cerebral cortex, cranial nerves, cerebral blood vessels, spinal cord, and nerve roots. Bacterial Meningitis,Bacterial Meningitides,Meningitides, Bacterial

Related Publications

Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Bacterial meningitis in Angola.
May 2003, Lancet (London, England),
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Bacterial meningitis and septicemia in sickle cell disease.
July 1977, American journal of diseases of children (1960),
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Bacterial blood cultures in children with sickle cell disease.
May 2010, The American journal of emergency medicine,
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
[Bacterial infections in children with sickle cell disease in Libreville].
October 1999, Archives de pediatrie : organe officiel de la Societe francaise de pediatrie,
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Susceptibility to invasive bacterial infections in children with sickle cell disease.
September 2010, Pediatric blood & cancer,
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
[Current bacterial causes of osteomyelitis in children with sickle cell disease].
January 2008, Sante (Montrouge, France),
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Invasive Bacterial Infections in Children With Sickle Cell Disease: 2014-2019.
October 2023, Pediatrics,
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Severe Acute Bacterial Infections in Children With Sickle Cell Disease in Togo.
October 2023, Journal of pediatric hematology/oncology,
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Incidence of serious bacterial infections in febrile children with sickle cell disease.
July 2013, Clinical pediatrics,
Tuula Pelkonen, and Irmeli Roine, and Luis Bernardino, and Kirsi Jahnukainen, and Heikki Peltola
Does Procalcitonin Predict Bacterial Infection in Febrile Children with Sickle Cell Disease?
January 2019, Indian journal of pediatrics,
Copied contents to your clipboard!