[Clinical efficacy of ct-guided transthoracic needle biopsy of peripheral lung lesions]. 2022

Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
Moscow City Oncology Hospital No. 1, Moscow, Russia.

OBJECTIVE To evaluate the effectiveness of a step-by-step protocol for GT-guided transthoracic biopsy in verification of peripheral lung tumors. METHODS A retrospective analysis of the results of GT-guided transthoracic biopsies of focal lung neoplasms was performed between October 2019 and December 2020. The analysis included the results of 176 biopsies in 158 patients. RESULTS Primary biopsy was informative in 139 (87.97%) out of 158 patients. There were 155 (88.07%) informative and 21 (11.93%) non-informative biopsies. Lung adenocarcinoma was diagnosed in 41 (25.95%) patients, squamous cell carcinoma in 35 (22.15%) patients, and small cell carcinoma in 9 (5.7%) patients. There were 17 (10.76%) patients with uninformative biopsy results. Sensitivity, specificity and accuracy were 86%, 95.5%, and 87.8%, respectively. PPV was 98.9%, NPV - 58.3%. Various complications occurred after 65 (36.93%) out of 176 biopsies (95% CI 30.15-44.27). Pneumothorax followed by pleural drainage was detected after 8 (4.55%) biopsies. CONCLUSIONS Accuracy of a step-by-step protocol for transthoracic biopsy was 88% that is not inferior to similar results in large-scale studies devoted to specialized navigation systems.

UI MeSH Term Description Entries
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D008175 Lung Neoplasms Tumors or cancer of the LUNG. Cancer of Lung,Lung Cancer,Pulmonary Cancer,Pulmonary Neoplasms,Cancer of the Lung,Neoplasms, Lung,Neoplasms, Pulmonary,Cancer, Lung,Cancer, Pulmonary,Cancers, Lung,Cancers, Pulmonary,Lung Cancers,Lung Neoplasm,Neoplasm, Lung,Neoplasm, Pulmonary,Pulmonary Cancers,Pulmonary Neoplasm
D011030 Pneumothorax An accumulation of air or gas in the PLEURAL CAVITY, which may occur spontaneously or as a result of trauma or a pathological process. The gas may also be introduced deliberately during PNEUMOTHORAX, ARTIFICIAL. Pneumothorax, Primary Spontaneous,Pressure Pneumothorax,Primary Spontaneous Pneumothorax,Spontaneous Pneumothorax,Tension Pneumothorax,Pneumothorax, Pressure,Pneumothorax, Spontaneous,Pneumothorax, Tension,Spontaneous Pneumothorax, Primary
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001707 Biopsy, Needle Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed. Aspiration Biopsy,Puncture Biopsy,Aspiration Biopsies,Biopsies, Aspiration,Biopsies, Needle,Biopsies, Puncture,Biopsy, Aspiration,Biopsy, Puncture,Needle Biopsies,Needle Biopsy,Puncture Biopsies
D012189 Retrospective Studies Studies used to test etiologic hypotheses in which inferences about an exposure to putative causal factors are derived from data relating to characteristics of persons under study or to events or experiences in their past. The essential feature is that some of the persons under study have the disease or outcome of interest and their characteristics are compared with those of unaffected persons. Retrospective Study,Studies, Retrospective,Study, Retrospective
D012680 Sensitivity and Specificity Binary classification measures to assess test results. Sensitivity or recall rate is the proportion of true positives. Specificity is the probability of correctly determining the absence of a condition. (From Last, Dictionary of Epidemiology, 2d ed) Specificity,Sensitivity,Specificity and Sensitivity
D016896 Treatment Outcome Evaluation undertaken to assess the results or consequences of management and procedures used in combating disease in order to determine the efficacy, effectiveness, safety, and practicability of these interventions in individual cases or series. Rehabilitation Outcome,Treatment Effectiveness,Clinical Effectiveness,Clinical Efficacy,Patient-Relevant Outcome,Treatment Efficacy,Effectiveness, Clinical,Effectiveness, Treatment,Efficacy, Clinical,Efficacy, Treatment,Outcome, Patient-Relevant,Outcome, Rehabilitation,Outcome, Treatment,Outcomes, Patient-Relevant,Patient Relevant Outcome,Patient-Relevant Outcomes
D061705 Image-Guided Biopsy Conducting a biopsy procedure with the aid of a MEDICAL IMAGING modality. Imaging Guided Biopsy,Biopsies, Image-Guided,Biopsies, Imaging Guided,Biopsy, Image-Guided,Biopsy, Imaging Guided,Guided Biopsies, Imaging,Guided Biopsy, Imaging,Image Guided Biopsy,Image-Guided Biopsies,Imaging Guided Biopsies

Related Publications

Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
March 2014, Journal of vascular and interventional radiology : JVIR,
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
March 1997, Zhonghua zhong liu za zhi [Chinese journal of oncology],
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
January 1991, Cardiovascular and interventional radiology,
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
March 2012, Radiology and oncology,
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
January 1973, Investigative radiology,
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
December 2007, La Radiologia medica,
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
June 2011, Zhonghua zhong liu za zhi [Chinese journal of oncology],
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
April 1990, Investigative radiology,
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
November 2014, Chest,
Yu S Esakov, and I V Shrainer, and E I Kirpichnikova, and E A Kulikova, and L A Efteev, and Z G Tukvadze, and G V Khvedelidze, and V N Galkin
January 2009, BMJ case reports,
Copied contents to your clipboard!