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31P NMR spin-lattice (T1) and spin-spin (T2) relaxation times of phosphocreatine, ATP, inorganic phosphate, and phosphomonoesters have been measured in vivo at 4.7 T in rat brain and rat brain tumors implanted on nude mice. The relaxation data were acquired using a phase-cycled saturation-recovery spin-echo sequence. The problems associated with the phase modulation of the ATP lines by the homonuclear coupling constants were overcome by using selective refocusing pulses for the T2 measurements. In all the metabolites, large differences (1 to 2 orders of magnitude) are observed between the two relaxation times. T1 values in rat brain tumors are 30 to 90% longer than their counterparts in normal rat brain. T2 values follow the same trend with smaller variations except for phosphocreatine values which seem much less sensitive to the metabolic state of the tissues.
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
October 1987,
Cancer research,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
February 1990,
The Tohoku journal of experimental medicine,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
August 1991,
Journal of the neurological sciences,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
June 1988,
Radiology,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
November 2019,
Applied magnetic resonance,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
September 2014,
Chemphyschem : a European journal of chemical physics and physical chemistry,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
October 1991,
Schizophrenia research,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
May 1987,
Nihon Igaku Hoshasen Gakkai zasshi. Nippon acta radiologica,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
February 2016,
Magnetic resonance in medicine,
C Remy, and
J P Albrand, and
A L Benabid, and
M Decorps, and
M Jacrot, and
J Riondel, and
M F Foray
January 1984,
European neurology,
