[Malignant hormonally inactive adrenocortical tumor]. 1987

K K Poroshin, and B N Kudriavtsev

Criteria are discussed, that according to the literature data allow one to consider adrenocortical tumors without cell polymorphism and mitoses as malignant ones. Such criteria include a rapid tumor growth and its large dimensions, necrotic foci, invasion of blastomatous elements into the capsule and their presence in the vascular lumen. A 47-year old female patient is reported with a rapidly growing large neoplasm of the right adrenal. This adrenocortical tumor in spite of the fact that it lacks polymorphism and mitoses of cells is considered as a malignant one (prevalence of cells with an insignificant amount of lipids, extensive necrotic foci, capsular invasion and evidence of tumor cells in the vascular lumen).

UI MeSH Term Description Entries
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000302 Adrenal Cortex The outer layer of the adrenal gland. It is derived from MESODERM and comprised of three zones (outer ZONA GLOMERULOSA, middle ZONA FASCICULATA, and inner ZONA RETICULARIS) with each producing various steroids preferentially, such as ALDOSTERONE; HYDROCORTISONE; DEHYDROEPIANDROSTERONE; and ANDROSTENEDIONE. Adrenal cortex function is regulated by pituitary ADRENOCORTICOTROPIN. Cortex, Adrenal
D000306 Adrenal Cortex Neoplasms Tumors or cancers of the ADRENAL CORTEX. Adrenocortical Cancer,Cancer of Adrenal Cortex,Adrenal Cortex Cancer,Cancer of the Adrenal Cortex,Neoplasms, Adrenal Cortex,Adrenal Cortex Cancers,Adrenal Cortex Neoplasm,Adrenocortical Cancers,Cancer, Adrenal Cortex,Cancer, Adrenocortical,Cancers, Adrenal Cortex,Cancers, Adrenocortical,Neoplasm, Adrenal Cortex

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