Biomaterial Database

Ethanol-induced alteration in thiamin status of young turkey poults. 1987

B H Ali, and C M Czarnecki

The effect of ethanol on thiamin status was determined in the turkey poult, a new animal model for alcohol-induced cardiomyopathy in humans. The poults were given ethanol (4 to 5% v/v) in the drinking water for six weeks post-hatch. This treatment decreased body weights and increased significantly the relative weights of the hearts. Ethanol consumption increased significantly the blood concentrations of pyruvate and lactate, decreased the activity of erythrocyte transketolase (TK), and increased the stimulation of TK activity of thiamin pyrophosphate (TPP) in lyzed blood cells (TPP effect). These findings indicate that ethanol treatment has an adverse effect on the thiamin status of the turkey poult.

UI	MeSH Term	Description	Entries
D007773	Lactates	Salts or esters of LACTIC ACID containing the general formula CH3CHOHCOOR.
D008297	Male		Males
D009929	Organ Size	The measurement of an organ in volume, mass, or heaviness.	Organ Volume,Organ Weight,Size, Organ,Weight, Organ
D011773	Pyruvates	Derivatives of PYRUVIC ACID, including its salts and esters.
D001835	Body Weight	The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms.	Body Weights,Weight, Body,Weights, Body
D004912	Erythrocytes	Red blood cells. Mature erythrocytes are non-nucleated, biconcave disks containing HEMOGLOBIN whose function is to transport OXYGEN.	Blood Cells, Red,Blood Corpuscles, Red,Red Blood Cells,Red Blood Corpuscles,Blood Cell, Red,Blood Corpuscle, Red,Erythrocyte,Red Blood Cell,Red Blood Corpuscle
D006321	Heart	The hollow, muscular organ that maintains the circulation of the blood.	Hearts
D000431	Ethanol	A clear, colorless liquid rapidly absorbed from the gastrointestinal tract and distributed throughout the body. It has bactericidal activity and is used often as a topical disinfectant. It is widely used as a solvent and preservative in pharmaceutical preparations as well as serving as the primary ingredient in ALCOHOLIC BEVERAGES.	Alcohol, Ethyl,Absolute Alcohol,Grain Alcohol,Alcohol, Absolute,Alcohol, Grain,Ethyl Alcohol
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013831	Thiamine	3-((4-Amino-2-methyl-5-pyrimidinyl)methyl)-5-(2- hydroxyethyl)-4-methylthiazolium chloride.	Aneurin,Vitamin B 1,Thiamin,Thiamine Mononitrate,Vitamin B1,Mononitrate, Thiamine