Biomaterial Database

Advancements in Three Dimensional In-Vitro Cell Culture Models. 2022

Shreemoyee De, and Neetu Singh

Centre for Biomedical Engineering, Indian Institute of Technology Delhi, Hauz Khas, New Delhi, 110016, India.

The scientific field is observing a gradual shift from monolayer cultures to three-dimensional (3D) models, as they give a more relevant data in pre-clinical stages. This review summarizes the major techniques and materials used to develop 3D platforms, especially for cancer. It also discusses the challenges and some unresolved issues of the field and highlights some techniques that have made it to the market.

UI	MeSH Term	Description	Entries
D009369	Neoplasms	New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.	Benign Neoplasm,Cancer,Malignant Neoplasm,Tumor,Tumors,Benign Neoplasms,Malignancy,Malignant Neoplasms,Neoplasia,Neoplasm,Neoplasms, Benign,Cancers,Malignancies,Neoplasias,Neoplasm, Benign,Neoplasm, Malignant,Neoplasms, Malignant
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000087603	Cell Culture Techniques, Three Dimensional	Methods for growing cells in a way that they form three-dimensional shapes, such as on a three-dimensionally shaped substrate or as free-falling aggregates in stirred liquids.	3-D Cell Culture,3-Dimensional Cell Culture,3D Cell Culture,Scaffold 3D Cell Culture,Scaffold Cell Culture,Scaffold Cell Culture Techniques,Three-Dimensional Cell Culture,3 D Cell Culture,3 Dimensional Cell Culture,3-D Cell Cultures,3-Dimensional Cell Cultures,3D Cell Cultures,Cell Culture, 3-D,Cell Culture, 3-Dimensional,Cell Culture, 3D,Cell Culture, Scaffold,Cell Culture, Three-Dimensional,Cell Cultures, 3-D,Cell Cultures, 3-Dimensional,Cell Cultures, 3D,Cell Cultures, Scaffold,Cell Cultures, Three-Dimensional,Culture, 3-D Cell,Cultures, 3-D Cell,Cultures, 3D Cell,Scaffold Cell Cultures,Three Dimensional Cell Culture,Three-Dimensional Cell Cultures
D018929	Cell Culture Techniques	Methods for maintaining or growing CELLS in vitro.	Cell Culture,Cell Culture Technique,Cell Cultures,Culture Technique, Cell,Culture Techniques, Cell