Biomaterial Database

A prospective comparative study on the effectiveness of two different non-adherent polyurethane dressings on split-thickness skin graft donor sites. 2022

Darshini Devi Rajasegeran, and Fazila Aloweni, and Xinyi Lim, and Saranya Chandra Sekaran, and Cong Phong Nguyen, and Lei Zhang, and Li Pin Brenda Lim, and Shihui Ong, and Yee Onn Kok, and Si Jack Chong

Nursing Division, Singapore General Hospital, Outram Road, 169608, Singapore. Electronic address: darshini.devi.rajasegeran@sgh.com.sg.

OBJECTIVE To analyze differences in re-epithelization, exudate absorbency, ease and pain on dressing removal between ALLEVYN™ Non-Adhesive and Betaplast™ N. METHODS Patients admitted to the general ward undergoing split skin grafting were recruited. Allevyn and Betaplast were applied on the donor site. Exudate absorption was assessed daily using an absorbency grading chart. Dressing change was done on post-operative day five. Ease of dressing removal and pain score using the Wong-Baker Pain Scale was assessed. The percentage of re-epithelization for each dressing was assessed. RESULTS 30 patients were recruited. There was a statistically significant difference in exudate absorption on post-operative day 3 (z = -2.006, p = 0.045, T = 236) and post-operative day 4 (z = -2.026, p = 0.0143, T = 188), pain score (z = -2.861, p = 0.004, T = 180), ease of removal (z = -2.668, p = 0.008, T = 126) and re-epithelization (z = -2.566, p = 0.009, T = 336) between Betaplast and Allevyn. CONCLUSIONS Betaplast may have faster re-epithelization, better exudate absorption, and is easier to remove while minimizing discomfort as compared to Allevyn.

UI	MeSH Term	Description	Entries
D010146	Pain	An unpleasant sensation induced by noxious stimuli which are detected by NERVE ENDINGS of NOCICEPTIVE NEURONS.	Suffering, Physical,Ache,Pain, Burning,Pain, Crushing,Pain, Migratory,Pain, Radiating,Pain, Splitting,Aches,Burning Pain,Burning Pains,Crushing Pain,Crushing Pains,Migratory Pain,Migratory Pains,Pains, Burning,Pains, Crushing,Pains, Migratory,Pains, Radiating,Pains, Splitting,Physical Suffering,Physical Sufferings,Radiating Pain,Radiating Pains,Splitting Pain,Splitting Pains,Sufferings, Physical
D011140	Polyurethanes	A group of thermoplastic or thermosetting polymers containing polyisocyanate. They are used as ELASTOMERS, as coatings, as fibers and as foams.	Polyisocyanates,Ostamer,Pellethane,Spandex,Ostamers,Pellethanes,Polyisocyanate,Polyurethane,Spandices
D011446	Prospective Studies	Observation of a population for a sufficient number of persons over a sufficient number of years to generate incidence or mortality rates subsequent to the selection of the study group.	Prospective Study,Studies, Prospective,Study, Prospective
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001458	Bandages	Material used for wrapping or binding any part of the body.	Dressings,Bandage,Dressing
D014945	Wound Healing	Restoration of integrity to traumatized tissue.	Healing, Wound,Healings, Wound,Wound Healings
D016038	Skin Transplantation	The grafting of skin in humans or animals from one site to another to replace a lost portion of the body surface skin.	Dermatoplasty,Grafting, Skin,Transplantation, Skin,Dermatoplasties,Graftings, Skin,Skin Grafting,Skin Graftings,Skin Transplantations,Transplantations, Skin