-transparent.png){kind=logo}
The effect of somatostatin (GH-RIH) on gastric, pancreatic and biliary secretion was examined in the anesthetized rats. Intravenous infusion of the hormone, in graded doses ranging from 1 to 16 microgram/kg/hr, produced a dose dependent inhibition of pentagastrin, 1.5 microgram/kg/hr, induced acid secretion, reaching about 54% of control level at the dose of 16 microgram/kg/hr. Somatostatin, 4, 16 and 64 microgram/kg/hr, inhibited the pancreatic juice volume stimulated by intravenous injection of secretin, 1 u/kg, as a bolus. Somatostastin, 2, 8, 32 and 128 microgram/kg/30 min, did not change the bile flow rate in control period. Somatostatin may play a physiological role in the regulation of the secretory process of the stomach and pancreas.
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
September 1977,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
January 1983,
Research in experimental medicine. Zeitschrift fur die gesamte experimentelle Medizin einschliesslich experimenteller Chirurgie,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
November 1990,
Journal of pharmacological methods,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
January 2002,
Hepato-gastroenterology,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
January 1978,
Digestion,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
January 1975,
Upsala journal of medical sciences,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
September 1979,
Igaku kenkyu. Acta medica,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
October 1992,
Bioscience reports,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
September 1981,
Digestive diseases and sciences,
M Moriga, and
K Kojima, and
M Aono, and
H Uchino, and
H Yajima
July 1982,
Acta physiologica Scandinavica,
