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An ammonium ion-specific electrode system is evaluated for analysis of blood urea nitrogen from serum, plasma ultrafiltrate, or hemodialyzer dialysate fluid. The electrode shows a high sensitivity over clinically useful concentration ranges. Free serum ammonia, volatile amines, or urea ammonia after hydrolysis can be measured. In a double blind study excellent correlation was found for 187 blood urea nitrogen samples measured with the electrode with standard auto-analyzer techniques. Continuous monitoring of urea in dialysate fluid is described. Urea clearances were measured from dialysate effluent from an in vitro dialysis using conventional equipment. These values show excellent correlation to those from stnadard analysis methods. A continuous urea sensor for on-line hemodialysis application which can provide quantification of therapy is described.
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
January 2003,
Meditsinskaia tekhnika,
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
January 1993,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
January 1983,
Life support systems : the journal of the European Society for Artificial Organs,
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
August 1979,
Artificial organs,
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
January 2001,
Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia,
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
January 1995,
Contributions to nephrology,
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
January 1991,
Biosensors & bioelectronics,
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
July 1996,
Clinical chemistry,
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
January 2006,
ASAIO journal (American Society for Artificial Internal Organs : 1992),
E Klein, and
J G Montalvo, and
R Wawro, and
F F Holland, and
A Lebeouf
July 1996,
The Analyst,
