BIOMAT Database Logo BIOMAT Database Logo

Retrospective identification of Acanthamoeba culbertsoni in a case of amoebic meningoencephalitis. 1978

E Willaert, and A R Stevens, and G R Healy

Acanthamoeba culbertsoni was identified retrospectively in a case of amoebic meningoencephalitis, previously reported by Jager and Stamm (Lancet, 2, 1343, 1972). This is the second report of this species causing secondary infection in man. Positive results were obtained only with anti-A. culbertsoni sera when the brain sections were stained by the indirect immunofluorescence antibody test with various antisera produced against different Acanthamoeba species. Antiserum raised against purified plasma membranes of A. culbertsoni showed once more its highly specific diagnostic value.

UI MeSH Term Description Entries
D008297 Male Males
D008590 Meningoencephalitis An inflammatory process involving the brain (ENCEPHALITIS) and meninges (MENINGITIS), most often produced by pathogenic organisms which invade the central nervous system, and occasionally by toxins, autoimmune disorders, and other conditions. Cerebromeningitis,Encephalomeningitis,Cerebromeningitides,Encephalomeningitides,Meningoencephalitides
D002462 Cell Membrane The lipid- and protein-containing, selectively permeable membrane that surrounds the cytoplasm in prokaryotic and eukaryotic cells. Plasma Membrane,Cytoplasmic Membrane,Cell Membranes,Cytoplasmic Membranes,Membrane, Cell,Membrane, Cytoplasmic,Membrane, Plasma,Membranes, Cell,Membranes, Cytoplasmic,Membranes, Plasma,Plasma Membranes
D005455 Fluorescent Antibody Technique Test for tissue antigen using either a direct method, by conjugation of antibody with fluorescent dye (FLUORESCENT ANTIBODY TECHNIQUE, DIRECT) or an indirect method, by formation of antigen-antibody complex which is then labeled with fluorescein-conjugated anti-immunoglobulin antibody (FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT). The tissue is then examined by fluorescence microscopy. Antinuclear Antibody Test, Fluorescent,Coon's Technique,Fluorescent Antinuclear Antibody Test,Fluorescent Protein Tracing,Immunofluorescence Technique,Coon's Technic,Fluorescent Antibody Technic,Immunofluorescence,Immunofluorescence Technic,Antibody Technic, Fluorescent,Antibody Technics, Fluorescent,Antibody Technique, Fluorescent,Antibody Techniques, Fluorescent,Coon Technic,Coon Technique,Coons Technic,Coons Technique,Fluorescent Antibody Technics,Fluorescent Antibody Techniques,Fluorescent Protein Tracings,Immunofluorescence Technics,Immunofluorescence Techniques,Protein Tracing, Fluorescent,Protein Tracings, Fluorescent,Technic, Coon's,Technic, Fluorescent Antibody,Technic, Immunofluorescence,Technics, Fluorescent Antibody,Technics, Immunofluorescence,Technique, Coon's,Technique, Fluorescent Antibody,Technique, Immunofluorescence,Techniques, Fluorescent Antibody,Techniques, Immunofluorescence,Tracing, Fluorescent Protein,Tracings, Fluorescent Protein
D006249 Hartmannella A genus of free-living amoebae found in fresh water. The cysts usually pass harmlessly through the intestinal tract of man and may thus be found in feces. Occasionally, these organisms cause respiratory tract infections or generalized fatal meningoencephalitis. Hartmannellas
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000918 Antibody Specificity The property of antibodies which enables them to react with some ANTIGENIC DETERMINANTS and not with others. Specificity is dependent on chemical composition, physical forces, and molecular structure at the binding site. Antibody Specificities,Specificities, Antibody,Specificity, Antibody

Related Publications

E Willaert, and A R Stevens, and G R Healy
Immunization with killed Acanthamoeba culbertsoni antigen and amoeba culture supernatant antigen in experimental Acanthamoeba meningoencephalitis.
January 1984, Transactions of the Royal Society of Tropical Medicine and Hygiene,
E Willaert, and A R Stevens, and G R Healy
[Amoebic meningoencephalitis by "Eaegleria" and "Acanthamoeba" (author's transl)].
January 1977, Annali Sclavo; rivista di microbiologia e di immunologia,
E Willaert, and A R Stevens, and G R Healy
[Primary amoebic meningoencephalitis: a case report].
January 2004, Revista de neurologia,
E Willaert, and A R Stevens, and G R Healy
Polyamine metabolism in Acanthamoeba culbertsoni.
January 1993, Microbios,
E Willaert, and A R Stevens, and G R Healy
Sterols of Acanthamoeba culbertsoni strain A-1.
January 1988, Steroids,
E Willaert, and A R Stevens, and G R Healy
Pathologic quiz case. Progressive fatal encephalopathy in an immunosuppressed patient with a history of discoid lupus erythematosus. Subacute granulomatous meningoencephalitis (Acanthamoeba culbertsoni).
September 2004, Archives of pathology & laboratory medicine,
E Willaert, and A R Stevens, and G R Healy
Identification of differentially expressed cDNAs in Acanthamoeba culbertsoni after mouse brain passage.
March 2006, The Korean journal of parasitology,
E Willaert, and A R Stevens, and G R Healy
Amoebic meningoencephalitis.
May 1977, The Journal of the Florida Medical Association,
E Willaert, and A R Stevens, and G R Healy
Amoebic meningoencephalitis.
July 1968, Science (New York, N.Y.),
E Willaert, and A R Stevens, and G R Healy
Maintenance of Acanthamoeba culbertsoni by cryopreservation.
December 1998, The Journal of parasitology,
Copied contents to your clipboard!