Fractures to the maxillofacial region can have a serious impact on quality of life. The over-representation of males in the occurrence of almost all types and mechanisms of these injuries has tended to divert attention away from maxillofacial fractures in females. This study aimed to describe trends in maxillofacial trauma in a New Zealand tertiary trauma centre over a 12 year period, with a particular focus on gender differences. A retrospective audit was undertaken of records for maxillofacial fracture cases referred to Dunedin Hospital and Southland Hospital Maxillofacial Units during the period January 2009 to December 2020. Information on age, gender and ethnicity, aetiology, alcohol and/or drug involvement, fracture type, and management was obtained from the Southern District Health Board - Health Connect South Network. Over the observation period, 1,561 patients presented for a total of 2,480 fractures. There was an increase in the proportion of fractures arising from falls and involving the orbit, while those due to interpersonal violence (IPV) or involving the mandible fell. Additionally, the proportion of cases treated conservatively rose, while the use of surgical fixation fell. While overall just over one in five patients were female, that proportion increased from one in six in 2009-2011 to one in four in 2018-2020. Fractures among females were due mainly to falls (55.6%) and road traffic accidents (23.2%), and frequently involved the orbit (46.3%). The proportion of presentations involving people aged 50 or older also increased over time. A greater proportion of women are suffering from facial fractures in the past decade than they have previously. Public health interventions for those at risk and their families are necessary. Interventions should have a focus on preventing falls and domestic violence, with a particular focus on older people and Māori/Pasifika populations. Improved and continued monitoring of these changing patterns is important for addressing the issues they present to New Zealand.