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Tests for Igm antibody to hepatitis B core antigen (anti-HBc IgM) are useful diagnostic tools in the evaluation of patients with hepatitis B virus (HBV) infection. A method is described for detecting anti-HBc IgM based on application of a commercially available radioimmunoassay for total anti-HBc to column separated serum IgM and the technique is evaluated in patients with acute and chronic HBV infection. Our test is both sensitive and specific for diagnosing acute hepatitis B, although duration of positivity is highly variable. This technique is simple, inexpensive, and might be particularly useful for laboratories performing limited numbers of examinations, or with limited resources. A 45 percent savings in reagent costs is realized in our laboratory.
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
July 1986,
Radioisotopes,
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
February 1985,
Radioisotopes,
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
July 1984,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
January 1984,
Gastroenterology,
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
January 1992,
Archives of virology. Supplementum,
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
January 1984,
Hepatology (Baltimore, Md.),
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
September 1986,
Journal of Korean medical science,
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
January 1983,
Hepatology (Baltimore, Md.),
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
April 1981,
The Journal of hygiene,
K M De Cock, and
M Ashcavai, and
S Govindarajan, and
A G Redeker
July 1985,
Mayo Clinic proceedings,
