-transparent.png){kind=logo}
beta-Aminoisobutyric acid (beta-AIB), a normal degradation product of thymine, a constituent of DNA and, to a lesser extent, of transfer RNA, is excreted in low levels in human urine. We found that a group of iron workers occupationally exposed to inorganic lead excreted high levels of urinary beta-AIB. Elevated urinary excretion of beta-AIB was also observed in marmosets, Callithrix jacchus, that received lead acetate in drinking water. Our results suggest that increased urinary excretion of beta-AIB could stem from damage to DNA on exposure to lead.
Related Publications
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
March 1969,
Journal of clinical pathology,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
June 1956,
American journal of human genetics,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
January 2004,
Rinsho byori. The Japanese journal of clinical pathology,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
May 1992,
British journal of industrial medicine,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
June 1953,
Annals of eugenics,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
February 1971,
Indian journal of medical sciences,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
January 1969,
Human heredity,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
January 1956,
Acta genetica et statistica medica,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
March 1978,
Clinica chimica acta; international journal of clinical chemistry,
W R Farkas, and
A Fischbein, and
S Solomon, and
F Buschman, and
E Borek, and
O K Sharma
January 1959,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
