BIOMAT Database Logo BIOMAT Database Logo

Calcium-dependent protein phosphorylation during secretion by exocytosis in the mast cell. 1978

W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard

UI MeSH Term Description Entries
D007700 Kinetics The rate dynamics in chemical or physical systems.
D008297 Male Males
D008407 Mast Cells Granulated cells that are found in almost all tissues, most abundantly in the skin and the gastrointestinal tract. Like the BASOPHILS, mast cells contain large amounts of HISTAMINE and HEPARIN. Unlike basophils, mast cells normally remain in the tissues and do not circulate in the blood. Mast cells, derived from the bone marrow stem cells, are regulated by the STEM CELL FACTOR. Basophils, Tissue,Basophil, Tissue,Cell, Mast,Cells, Mast,Mast Cell,Tissue Basophil,Tissue Basophils
D008970 Molecular Weight The sum of the weight of all the atoms in a molecule. Molecular Weights,Weight, Molecular,Weights, Molecular
D010766 Phosphorylation The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety. Phosphorylations
D011506 Proteins Linear POLYPEPTIDES that are synthesized on RIBOSOMES and may be further modified, crosslinked, cleaved, or assembled into complex proteins with several subunits. The specific sequence of AMINO ACIDS determines the shape the polypeptide will take, during PROTEIN FOLDING, and the function of the protein. Gene Products, Protein,Gene Proteins,Protein,Protein Gene Products,Proteins, Gene
D002118 Calcium A basic element found in nearly all tissues. It is a member of the alkaline earth family of metals with the atomic symbol Ca, atomic number 20, and atomic weight 40. Calcium is the most abundant mineral in the body and combines with phosphorus to form calcium phosphate in the bones and teeth. It is essential for the normal functioning of nerves and muscles and plays a role in blood coagulation (as factor IV) and in many enzymatic processes. Coagulation Factor IV,Factor IV,Blood Coagulation Factor IV,Calcium-40,Calcium 40,Factor IV, Coagulation
D003189 p-Methoxy-N-methylphenethylamine A potent mast cell degranulator. It is involved in histamine release. Agent 48-80,BW 48-80,Compound 48-80,Preparation 48-80,Agent 48 80,Agent 4880,BW 48 80,BW 4880,Compound 48 80,Compound 4880,Preparation 48 80,Preparation 4880,p Methoxy N methylphenethylamine
D005089 Exocytosis Cellular release of material within membrane-limited vesicles by fusion of the vesicles with the CELL MEMBRANE.
D000001 Calcimycin An ionophorous, polyether antibiotic from Streptomyces chartreusensis. It binds and transports CALCIUM and other divalent cations across membranes and uncouples oxidative phosphorylation while inhibiting ATPase of rat liver mitochondria. The substance is used mostly as a biochemical tool to study the role of divalent cations in various biological systems. 4-Benzoxazolecarboxylic acid, 5-(methylamino)-2-((3,9,11-trimethyl-8-(1-methyl-2-oxo-2-(1H-pyrrol-2-yl)ethyl)-1,7-dioxaspiro(5.5)undec-2-yl)methyl)-, (6S-(6alpha(2S*,3S*),8beta(R*),9beta,11alpha))-,A-23187,A23187,Antibiotic A23187,A 23187,A23187, Antibiotic

Related Publications

W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
[Protein phosphorylation during mast cell secretion in radioprophylaxis].
January 1990, Radiobiologiia,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
The mechanism of exocytosis during secretion in mast cells.
January 1989, Society of General Physiologists series,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
Calcium- and guanine-nucleotide-dependent exocytosis in permeabilized rat mast cells. Modulation by protein kinase C.
January 1990, The Biochemical journal,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
Proceedings: Mast cell secretion (histamine release) induced by 48-80: calcium-dependent exocytosis inhibited strongly by cytochalasin only when glycolysis is rate-limiting.
October 1973, The Journal of physiology,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
Phosphorylation of SNAP-23 regulates its dynamic membrane association during mast cell exocytosis.
September 2017, Biology open,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
Calcium and stimulus-secretion coupling in the mast cell: stimulant and inhibitory effects of calcium-rich media on exocytosis.
September 1977, The Journal of physiology,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
Calcium-dependent vesicular exocytosis: from constitutive to regulated secretion.
January 1995, Cold Spring Harbor symposia on quantitative biology,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
[The role of protein phosphorylation in mast cell secretion, stimulated by concanavalin A. Connection to the cytoskeleton].
September 1989, Biokhimiia (Moscow, Russia),
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
The ins and outs of IgE-dependent mast-cell exocytosis.
May 2004, Trends in immunology,
W Sieghart, and T C Theoharides, and S L Alper, and W W Douglas, and P Greengard
MYO1F Regulates IgE and MRGPRX2-Dependent Mast Cell Exocytosis.
May 2021, Journal of immunology (Baltimore, Md. : 1950),
Copied contents to your clipboard!