Biomaterial Database

[Clinical and laboratory evaluation of the results of treating trophic ulcers of the lower extremities with a catgut dressing]. 1978

V G Sashchikova, and I V Kunitsina, and A D Ostrovskiĭ

To assess the effect of the catgut dressing in trophic ulcers of the lower extremities upon the dynamics of non-specific immunological reactivity the authors defined the complementary activity of the serum, concentration of the serumal lysozyme and contents of thermolabile inhibitors of the serum. The clinical and laboratory findings prove that the use of the cargut dressing in trophic ulcers of the lower extremities increases the level of non-specific immunological reactivity of an organism. The use of catgut for the therapeutic purposes stimulates the condition of natural immunity which constitutes one of the causes contributing to a favourable course of the healing processes.

UI	MeSH Term	Description	Entries
D007113	Immunity, Innate	The capacity of a normal organism to remain unaffected by microorganisms and their toxins. It results from the presence of naturally occurring ANTI-INFECTIVE AGENTS, constitutional factors such as BODY TEMPERATURE and immediate acting immune cells such as NATURAL KILLER CELLS.	Immunity, Native,Immunity, Natural,Immunity, Non-Specific,Resistance, Natural,Innate Immune Response,Innate Immunity,Immune Response, Innate,Immune Responses, Innate,Immunity, Non Specific,Innate Immune Responses,Native Immunity,Natural Immunity,Natural Resistance,Non-Specific Immunity
D007871	Leg Ulcer	Ulceration of the skin and underlying structures of the lower extremity. About 90% of the cases are due to venous insufficiency (VARICOSE ULCER), 5% to arterial disease, and the remaining 5% to other causes.	Leg Ulcers,Ulcer, Leg,Ulcers, Leg
D008297	Male		Males
D002398	Catgut	Sterile collagen strands obtained from healthy mammals. They are used as absorbable surgical ligatures and are frequently impregnated with chromium or silver for increased strength. They tend to cause tissue reaction.	Catguts
D002908	Chronic Disease	Diseases which have one or more of the following characteristics: they are permanent, leave residual disability, are caused by nonreversible pathological alteration, require special training of the patient for rehabilitation, or may be expected to require a long period of supervision, observation, or care (Dictionary of Health Services Management, 2d ed). For epidemiological studies chronic disease often includes HEART DISEASES; STROKE; CANCER; and diabetes (DIABETES MELLITUS, TYPE 2).	Chronic Condition,Chronic Illness,Chronically Ill,Chronic Conditions,Chronic Diseases,Chronic Illnesses,Condition, Chronic,Disease, Chronic,Illness, Chronic
D002986	Clinical Trials as Topic	Works about pre-planned studies of the safety, efficacy, or optimum dosage schedule (if appropriate) of one or more diagnostic, therapeutic, or prophylactic drugs, devices, or techniques selected according to predetermined criteria of eligibility and observed for predefined evidence of favorable and unfavorable effects. This concept includes clinical trials conducted both in the U.S. and in other countries.	Clinical Trial as Topic
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013537	Sutures	Materials used in closing a surgical or traumatic wound. (From Dorland, 28th ed)	Staples, Surgical,Surgical Staples,Staple, Surgical,Surgical Staple,Suture
D064987	Cell- and Tissue-Based Therapy	Therapies that involve the TRANSPLANTATION of CELLS or TISSUES developed for the purpose of restoring the function of diseased or dysfunctional cells or tissues.	Cell Therapy,Tissue Therapy,Therapy, Cell,Therapy, Tissue,Cell and Tissue Based Therapy