Biomaterial Database

Immunity to Eimeria separata (Apicomplexa: Eimeriina): expose-and-challenge studies in rats. 1987

W C Marquardt, and B A Pafume, and D Bush

Oocyst production of Eimeria separata of the rat was determined in initial and challenge infections. The total number of oocysts produced was no higher at 100 oocysts than at 1,000, 10,000, or 100,000 in initial infections. In 2 experiments, the reproductive index with 100 oocysts was 17,000 and 34,000, respectively. On challenge with 10,000 oocysts, there was 91% protection at 100 oocysts. There was slightly lower protection at 10,000 and 100,000 oocysts, 72% and 81%, respectively, and t-values suggest lower protection at these higher inocula.

UI	MeSH Term	Description	Entries
D007110	Immunity, Active	Resistance to a disease agent resulting from the production of specific antibodies by the host, either after exposure to the disease or after vaccination.	Active Immune Response,Active Immune Responses,Active Immunities,Active Immunity,Immune Response, Active,Immune Responses, Active,Immunities, Active,Response, Active Immune,Responses, Active Immune
D003048	Coccidiosis	Protozoan infection found in animals and man. It is caused by several different genera of COCCIDIA.	Besnoitiasis,Besnoitiosis,Besnoitiases,Besnoitioses,Coccidioses
D004539	Eimeria	A genus of protozoan parasites of the subclass COCCIDIA. Various species are parasitic in the epithelial cells of the liver and intestines of man and other animals.	Eimerias
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D051381	Rats	The common name for the genus Rattus.	Rattus,Rats, Laboratory,Rats, Norway,Rattus norvegicus,Laboratory Rat,Laboratory Rats,Norway Rat,Norway Rats,Rat,Rat, Laboratory,Rat, Norway,norvegicus, Rattus