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gamma-Amino[2,3-3H]butyric acid ([3H]GABA) transport was investigated in hippocampal synaptosomes prepared from amygdala kindled rats. Kindling enhanced [3H]GABA uptake by 10-20%, while the Km of uptake and the kinetics of the release were unchanged. The dose response curve of the inhibition of [3H]GABA uptake by veratridine was altered by kindling: the K0.5 of inhibition and the Hill number increased and the curve became biphasic after a long period of stimulations. This effect was interpreted in terms of a modification of the functioning of the presynaptic fast Na+ channels which initially become more resistant to depolarization. In the long term, it appears that new Na+ channels develop that are more sensitive to the action of veratridine.
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
January 1989,
Experimental brain research,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
October 1999,
Alcoholism, clinical and experimental research,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
July 1985,
Experimental neurology,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
January 1982,
Experimental neurology,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
February 1997,
Journal of neurochemistry,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
January 2005,
Learning & memory (Cold Spring Harbor, N.Y.),
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
March 2013,
Neuropharmacology,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
January 1985,
Folia psychiatrica et neurologica japonica,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
May 2013,
Neuroscience letters,
I Chaudieu, and
G Rondouin, and
M Chicheportiche, and
R Chicheportiche
December 1987,
Experimental neurology,
