-transparent.png){kind=logo}
The location of 125I-iodotyrosyl gastrin I binding sites in rat gastric mucosa was studied. Peptide specificity was demonstrated by competitive binding studies through the addition of a large dose of cold human gastrin I or cholecystokinin-octapeptide. Autoradiography of the stomach tissue was carried out by freeze-drying, embedding in Epon, wet-sectioning with ethylene glycol, and dry-mounting the emulsion film by means of the wire-loop method to prevent loss of the labeled substance. Specific binding sites for gastrin were found on parietal and chief cells, whereas few binding sites were seen on the surface mucous or mucous neck cells. Binding sites on the parietal cells were dispersed in the cytoplasm, while those on the chief cells were found near the basal plasma membrane.
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
August 1988,
Scandinavian journal of gastroenterology,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
August 1982,
Neuroscience letters,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
January 1994,
Peptides,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
August 1990,
Biochemical and biophysical research communications,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
August 1989,
The American journal of physiology,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
January 1986,
Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
January 1974,
Surgical forum,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
June 1983,
Brain research,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
November 1993,
Cancer research,
M Nakamura, and
M Oda, and
K Kaneko, and
Y Yonei, and
N Tsukada, and
H Komatsu, and
M Tsugu, and
M Tsuchiya
June 1990,
Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology,
