Comparative virulence of some English strains of Haemophilus pleuropneumoniae serotypes 2 and 3 in the pig. 1987

S R Brandreth, and I M Smith

Between 10(7.5) and 10(8.1) viable organisms of four English and one Danish strain of Haemophilus pleuropneumoniae serotype 2 and five English strains of serotype 3 were inoculated intranasally into groups of conventional pigs. Among the English isolates of both serotypes there were virulent and non-virulent strains. Four of the serotype 2 strains, including the Danish strain, and two of the serotype 3 strains produced varying degrees of pulmonary consolidation with abscess formation and pleurisy in at least three of the five pigs in the individual groups. H pleuropneumoniae was isolated from the pulmonary lesions in all save one instance, frequently from the tonsil but less frequently from other parts of the respiratory tract. Purulent arthritis and tenosynovitis developed in one animal infected with serotype 3. Apart from the latter pig no clinical signs of illness were detected except for febrile reactions which reflected the prevalence of the thoracic lesions in the various groups. A humoral antibody response was detected by indirect immunofluorescence in two-thirds of the pigs which developed lesions but in fewer by complement fixation.

UI MeSH Term Description Entries
D001831 Body Temperature The measure of the level of heat of a human or animal. Organ Temperature,Body Temperatures,Organ Temperatures,Temperature, Body,Temperature, Organ,Temperatures, Body,Temperatures, Organ
D001835 Body Weight The mass or quantity of heaviness of an individual. It is expressed by units of pounds or kilograms. Body Weights,Weight, Body,Weights, Body
D003718 Denmark A country in northern Europe, bordering the Baltic Sea and the North Sea. The capital is Copenhagen. Faeroe Islands,Faroe Islands
D004739 England A part of Great Britain within the United Kingdom.
D005260 Female Females
D006190 Haemophilus A genus of PASTEURELLACEAE that consists of several species occurring in animals and humans. Its organisms are described as gram-negative, facultatively anaerobic, coccobacillus or rod-shaped, and nonmotile. Hemophilus
D006192 Haemophilus Infections Infections with bacteria of the genus HAEMOPHILUS. Hemophilus Infections,Haemophilus influenzae Infection,Haemophilus influenzae Type b Infection,Hib Infection,Infections, Haemophilus,Infections, Hemophilus,Haemophilus Infection,Haemophilus influenzae Infections,Hemophilus Infection,Hib Infections,Infection, Haemophilus,Infection, Haemophilus influenzae,Infection, Hemophilus,Infection, Hib
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000907 Antibodies, Bacterial Immunoglobulins produced in a response to BACTERIAL ANTIGENS. Bacterial Antibodies
D013552 Swine Any of various animals that constitute the family Suidae and comprise stout-bodied, short-legged omnivorous mammals with thick skin, usually covered with coarse bristles, a rather long mobile snout, and small tail. Included are the genera Babyrousa, Phacochoerus (wart hogs), and Sus, the latter containing the domestic pig (see SUS SCROFA). Phacochoerus,Pigs,Suidae,Warthogs,Wart Hogs,Hog, Wart,Hogs, Wart,Wart Hog

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