BIOMAT Database Logo BIOMAT Database Logo

Measurement of serum glycosylated proteins and glycosylated low density lipoprotein fraction in diabetes mellitus. 1987

I Mani, and J Patel, and U V Mani

A simple method was developed for estimating serum glycosylated protein levels using gel filtration with Bio-Gel P6 by determining the protein and sugar content in the void volume fraction. The glycosylated protein levels (GSP) correlated well with fasting blood sugar levels and glycosylated albumin level (G-ALB) determined by affinity chromatography with Blue Sepharose CL6B. The glycosylation level of heparin-citrate precipitable fraction of serum which predominantly contained low density lipoprotein (G-LDL) also correlated well with GSP and LDL-cholesterol levels. Significantly different values were obtained for GSP, G-ALB, and G-LDL between normals and diabetics.

UI MeSH Term Description Entries
D008077 Lipoproteins, LDL A class of lipoproteins of small size (18-25 nm) and light (1.019-1.063 g/ml) particles with a core composed mainly of CHOLESTEROL ESTERS and smaller amounts of TRIGLYCERIDES. The surface monolayer consists mostly of PHOSPHOLIPIDS, a single copy of APOLIPOPROTEIN B-100, and free cholesterol molecules. The main LDL function is to transport cholesterol and cholesterol esters to extrahepatic tissues. Low-Density Lipoprotein,Low-Density Lipoproteins,beta-Lipoprotein,beta-Lipoproteins,LDL(1),LDL(2),LDL-1,LDL-2,LDL1,LDL2,Low-Density Lipoprotein 1,Low-Density Lipoprotein 2,LDL Lipoproteins,Lipoprotein, Low-Density,Lipoproteins, Low-Density,Low Density Lipoprotein,Low Density Lipoprotein 1,Low Density Lipoprotein 2,Low Density Lipoproteins,beta Lipoprotein,beta Lipoproteins
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D001786 Blood Glucose Glucose in blood. Blood Sugar,Glucose, Blood,Sugar, Blood
D001798 Blood Proteins Proteins that are present in blood serum, including SERUM ALBUMIN; BLOOD COAGULATION FACTORS; and many other types of proteins. Blood Protein,Plasma Protein,Plasma Proteins,Serum Protein,Serum Proteins,Protein, Blood,Protein, Plasma,Protein, Serum,Proteins, Blood,Proteins, Plasma,Proteins, Serum
D002784 Cholesterol The principal sterol of all higher animals, distributed in body tissues, especially the brain and spinal cord, and in animal fats and oils. Epicholesterol
D002850 Chromatography, Gel Chromatography on non-ionic gels without regard to the mechanism of solute discrimination. Chromatography, Exclusion,Chromatography, Gel Permeation,Chromatography, Molecular Sieve,Gel Filtration,Gel Filtration Chromatography,Chromatography, Size Exclusion,Exclusion Chromatography,Gel Chromatography,Gel Permeation Chromatography,Molecular Sieve Chromatography,Chromatography, Gel Filtration,Exclusion Chromatography, Size,Filtration Chromatography, Gel,Filtration, Gel,Sieve Chromatography, Molecular,Size Exclusion Chromatography
D003920 Diabetes Mellitus A heterogeneous group of disorders characterized by HYPERGLYCEMIA and GLUCOSE INTOLERANCE.
D006023 Glycoproteins Conjugated protein-carbohydrate compounds including MUCINS; mucoid, and AMYLOID glycoproteins. C-Glycosylated Proteins,Glycosylated Protein,Glycosylated Proteins,N-Glycosylated Proteins,O-Glycosylated Proteins,Glycoprotein,Neoglycoproteins,Protein, Glycosylated,Proteins, C-Glycosylated,Proteins, Glycosylated,Proteins, N-Glycosylated,Proteins, O-Glycosylated
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000093422 Glycated Serum Proteins Proteins in serum that have undergone, in vivo, non-enzymatic modification with reducing sugars via the MAILLARD REACTION. They are analyzed to measure control of HYPERGLYCEMIA. Glycated Blood Protein,Glycated Blood Proteins,Glycated Serum Protein,Glycosylated Blood Protein,Glycosylated Blood Proteins,Glycosylated Serum Protein,Glycosylated Serum Proteins,Serum Protein, Glycated,Serum Protein, Glycosylated,Blood Protein, Glycated,Blood Protein, Glycosylated,Blood Proteins, Glycated,Blood Proteins, Glycosylated,Protein, Glycated Blood,Protein, Glycosylated Blood,Proteins, Glycated Blood,Proteins, Glycosylated Blood,Proteins, Glycosylated Serum,Serum Proteins, Glycated,Serum Proteins, Glycosylated

Related Publications

I Mani, and J Patel, and U V Mani
Measurement of receptor-independent metabolism of low-density lipoprotein. An application of glycosylated low-density lipoprotein.
April 1983, European journal of biochemistry,
I Mani, and J Patel, and U V Mani
[Non-enzymatically glycosylated low-density lipoproteins in diabetes mellitus].
January 1987, Vutreshni bolesti,
I Mani, and J Patel, and U V Mani
[Analysis of glycosylated proteins and serum fructosamine in diabetes mellitus].
December 1986, Orvosi hetilap,
I Mani, and J Patel, and U V Mani
[Diabetes mellitus and glycosylated proteins].
August 1982, Rinsho byori. The Japanese journal of clinical pathology,
I Mani, and J Patel, and U V Mani
[Glycosylated serum proteins in the early diagnosis of diabetes mellitus].
January 1988, Vutreshni bolesti,
I Mani, and J Patel, and U V Mani
[Malondialdehyde-modified-low density lipoprotein in diabetes mellitus].
March 1991, Hua xi yi ke da xue xue bao = Journal of West China University of Medical Sciences = Huaxi yike daxue xuebao,
I Mani, and J Patel, and U V Mani
Very low density lipoprotein metabolism in diabetes mellitus.
April 1987, Diabetes/metabolism reviews,
I Mani, and J Patel, and U V Mani
Increased electronegative charge of serum low-density lipoprotein in patients with diabetes mellitus.
February 2004, Clinica chimica acta; international journal of clinical chemistry,
I Mani, and J Patel, and U V Mani
Abnormal metabolism of low density lipoprotein in diabetes mellitus.
January 1985, Hormone and metabolic research. Supplement series,
I Mani, and J Patel, and U V Mani
[Glycosylated blood proteins in diabetes mellitus].
October 1982, Klinicheskaia meditsina,
Copied contents to your clipboard!