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The teratogenicity of a commercial formulation of the fungicide maneb (Maneb 80, containing 80% manganese ethylenebisdithiocarbamate and 20% inert ingredients) in chick embryos was evaluated. Unincubated eggs (157-207 per treatment group) were immersed in 0.5, 1.5, 4.5, or 13.5 g/liter maneb aqueous solutions for 30 sec. Two control groups were used: one group of 200 eggs was immersed in tap water and a second group of 205 eggs was immersed in a solution of the inert ingredients (sodium lignin sulfonate and n-butylnaphthalene sulfonate) at the concentration present in the 13.5 g/liter maneb solution. Eggs were then incubated for 19 days. A single treatment with maneb was teratogenic at all concentrations tested, producing mainly unilateral lower limb deformities. No adverse effects on development were noticed after exposure to the inert ingredients.
R Maci, and
E Arias
February 1989,
Ecotoxicology and environmental safety,
R Maci, and
E Arias
January 1985,
Veterinarno-meditsinski nauki,
R Maci, and
E Arias
April 1966,
Journal of embryology and experimental morphology,
R Maci, and
E Arias
January 1990,
Anatomischer Anzeiger,
R Maci, and
E Arias
October 1988,
Mutation research,
R Maci, and
E Arias
August 1964,
Acta chirurgiae orthopaedicae et traumatologiae Cechoslovaca,
R Maci, and
E Arias
January 1964,
Acta morphologica Neerlando-Scandinavica,
R Maci, and
E Arias
April 2011,
JPMA. The Journal of the Pakistan Medical Association,
R Maci, and
E Arias
April 1975,
Teratology,
