-transparent.png){kind=logo}
Natural killer (NK) cell activity was investigated in 24 patients who were undergoing minor gynaecological surgery performed during neurolept, halothane or spinal anaesthesia. The endocrine response to anaesthesia and surgery was monitored using serum cortisol and plasma catecholamine estimations. The surgical trauma was insufficient to elicit an endocrine stress response. No changes in NK cell cytotoxicity occurred in any group during premedication, anaesthesia or surgery. Post-operatively the NK cell activity fell transiently in the two groups that received general anaesthesia (P less than 0.05), whereas no reduction was found in the group that was given spinal anaesthesia. The results indicate that minor surgery induces only small variations in NK cell cytotoxicity and no conclusions can be made, therefore, concerning the influence of different anaesthetic techniques on NK cell cytotoxicity.
E Tøonnesen, and
M S Hüttel, and
N J Christensen
December 1984,
Acta anaesthesiologica Scandinavica,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
April 1995,
Natural immunity,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
January 1998,
Hormone research,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
October 1984,
Acta anaesthesiologica Scandinavica,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
March 1989,
British journal of anaesthesia,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
December 1997,
Orvosi hetilap,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
December 1987,
Chest,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
May 1989,
Taiwan yi xue hui za zhi. Journal of the Formosan Medical Association,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
August 1994,
Immunological investigations,
E Tøonnesen, and
M S Hüttel, and
N J Christensen
June 1983,
Acta anaesthesiologica Scandinavica,
