-transparent.png){kind=logo}
Patient records from January 1975 to December 1984 were analysed to assess the possible incidence of protein-bound vitamin B12 malabsorption. This condition is characterised by a low serum vitamin B12 level and a normal Schilling test but impaired absorption of vitamin B12 bound to protein. We found that 48 (25%) patients with a low serum cobalamin level unexplained by other causes had a normal Schilling test. Megaloblastic haemopoiesis was found in 25 of these. From this group, all 10 patients who had a test of protein-bound vitamin B12 absorption showed impaired absorption. Protein-bound vitamin B12 malabsorption may represent an early phase of pernicious anaemia when hypochlorhydria precedes intrinsic factor deficiency and should be tested for when the serum vitamin B12 level is decreased and the Schilling test is normal.
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
March 1984,
British medical journal (Clinical research ed.),
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
May 1979,
Digestive diseases and sciences,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
November 1960,
The American journal of digestive diseases,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
October 1991,
Gastroenterology,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
March 1990,
Nederlands tijdschrift voor geneeskunde,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
November 1994,
Clinical nuclear medicine,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
July 1963,
Acta haematologica,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
April 1985,
Nutrition reviews,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
December 1989,
Gut,
B P Jones, and
A F Broomhead, and
Y L Kwan, and
C S Grace
January 2022,
Vitamins and hormones,
