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Intracellular excitatory postsynaptic potentials (EPSPs) were recorded in area CA1 of hippocampal slices from guinea pigs. With paired-pulse stimulation of stratum radiatum, the second stimulus (interval of 40-50 ms) produced an EPSP with enlarged amplitude. Two methods of quantal analysis showed an increase in quantal content of the facilitated EPSP and a smaller increase in quantal size. The correlation between amplitudes of the first and second EPSP was usually insignificant. The results favour a presynaptic location of the mechanisms of the paired-pulse facilitation and suggest increases in the average of transmitter quanta released by presynaptic volley as well as increases in the amount of transmitter in each quantum.
G Hess, and
U Kuhnt, and
L L Voronin
September 1994,
Neuroscience,
G Hess, and
U Kuhnt, and
L L Voronin
May 2002,
Neuropharmacology,
G Hess, and
U Kuhnt, and
L L Voronin
January 1986,
Neuroscience letters,
G Hess, and
U Kuhnt, and
L L Voronin
January 2004,
Proceedings of the National Academy of Sciences of the United States of America,
G Hess, and
U Kuhnt, and
L L Voronin
June 1992,
Brain research,
G Hess, and
U Kuhnt, and
L L Voronin
August 1998,
Epilepsy research,
G Hess, and
U Kuhnt, and
L L Voronin
October 1992,
Neuroscience letters,
G Hess, and
U Kuhnt, and
L L Voronin
February 1997,
Neuroscience,
G Hess, and
U Kuhnt, and
L L Voronin
April 1997,
Neuroscience research,
G Hess, and
U Kuhnt, and
L L Voronin
July 1994,
Brain research,
