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Infants Receiving Very Early Antiretroviral Therapy Have High CD4 Counts in the First Year of Life. 2023
Bryan S Nelson, and
Camlin Tierney, and
Deborah Persaud, and
Jennifer Jao, and
Mark F Cotton, and
Yvonne Bryson, and
Anne Coletti, and
Theodore D Ruel, and
Stephen A Spector, and
Christina Reding, and
Kira Bacon, and
Diane Costello, and
Charlotte Perlowski, and
Maria Leticia Santos Cruz, and
Josphat Kosgei, and
Sai Majji, and
Dwight E Yin, and
Patrick Jean-Philippe, and
Ellen G Chadwick, and
Center for Biostatistics in AIDS Research in the Department of Biostatistics, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.
We followed 54 infants with in utero HIV after initiating very early antiretroviral treatment. At weeks 24 and 48, ≥80% had CD4 ≥1500 cells/mm3 and CD4% ≥25%. Routine Pneumocystis jirovecii pneumonia prophylaxis in the first year of life may not be necessary for all very early treated infants. NCT02140255.
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