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Zinc nutriture and immune function were studied in 100 subjects, age 60-89 yr. Mean (+/- SD) zinc concentrations found were 84.8 +/- 15.5 micrograms/dL (13.0 +/- 2.4 microM) for plasma, 1.04 +/- 0.24 micrograms (0.016 +/- 0.004 mumol)/10(9) cells for erythrocytes, 4.06 +/- 1.85 micrograms (0.062 +/- 0.028 mumol)/10(9) cells for mononuclear cells, 3.91 +/- 1.77 micrograms (0.060 +/- 0.027 mumol)/10(9) cells for polymorphonuclear leukocytes, 0.53 +/- 0.39 micrograms (0.0081 +/- 0.0060 mumol)/10(9) cells for platelets, and 222 +/- 101 micrograms (3.39 +/- 1.54 mumol)/g for hair. Zinc ingestion was below the RDA in more than 90% of study subjects. The incidence of anergy to a panel of seven skin test antigens was 41%; responses to these antigens were significantly associated with the plasma zinc concentration. Subjects with depressed lymphocyte responses to mitogens had significantly lower platelet and significantly higher mononuclear cell zinc concentrations than those with normal responses.
J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
January 1988,
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J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
March 1985,
Geriatrics,
J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
March 1992,
The Journal of nutrition,
J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
January 1983,
International journal for vitamin and nutrition research. Internationale Zeitschrift fur Vitamin- und Ernahrungsforschung. Journal international de vitaminologie et de nutrition,
J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
June 1994,
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J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
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T N Denny, and
D B Louria
January 1977,
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J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
February 1986,
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J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
January 1990,
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J D Bogden, and
J M Oleske, and
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F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
January 2004,
The journal of nutrition, health & aging,
J D Bogden, and
J M Oleske, and
E M Munves, and
M A Lavenhar, and
K S Bruening, and
F W Kemp, and
K J Holding, and
T N Denny, and
D B Louria
August 1980,
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