Do hiatal expansion and levator avulsion have a role in causation of pelvic organ prolapse? 2022

Peter Petros
School of Engineering and Mathematical Sciences, University of Western Australia, 35 Stirling Highway, Perth, Western Australia, 6009, Australia.

OBJECTIVE To examine whether hiatal expansion and levator avulsion have a role in the causation of pelvic organ prolapse (POP). METHODS Data from studies which showed a strong association of hiatal expansion and levator avulsion were analysed for causation against an alternative view, POPcausation by ligament/connective tissue damage. RESULTS Some studies potentially fitted the "Regularity Theory of Causality"; i.e., an apparent cause, occurred with such regularity as to be considered a cause. However, these studies failed the logical requirement of "unconditional": all levator avulsions were to be followed directly by occurrence of POP, if the association were to be considered valid. Two studies which placed a large mesh behind the rectum and around puborectalis muscle greatly diminished levator expansion, but POP recurred in 78% of the women by 12 months. These results invalidated hypotheses of cause (levator expansion) and effect (prolapse). CONCLUSIONS Levator avulsion/hiatal expansion co-occurs with POP. The cause for both is likely inability of the birth canal to plasticize" sufficiently to prevent simultaneous damage to the hiatal muscles and surrounding fascias and ligaments, which explains the co-occurrence. Greater than 90% cure of POP by site-specific repair of up to 4 pelvic ligaments supported the alternative hypothesis of simultaneous damage to pelvic ligaments to cause prolapse.

UI MeSH Term Description Entries
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D014463 Ultrasonography The visualization of deep structures of the body by recording the reflections or echoes of ultrasonic pulses directed into the tissues. Use of ultrasound for imaging or diagnostic purposes employs frequencies ranging from 1.6 to 10 megahertz. Echography,Echotomography,Echotomography, Computer,Sonography, Medical,Tomography, Ultrasonic,Ultrasonic Diagnosis,Ultrasonic Imaging,Ultrasonographic Imaging,Computer Echotomography,Diagnosis, Ultrasonic,Diagnostic Ultrasound,Ultrasonic Tomography,Ultrasound Imaging,Diagnoses, Ultrasonic,Diagnostic Ultrasounds,Imaging, Ultrasonic,Imaging, Ultrasonographic,Imaging, Ultrasound,Imagings, Ultrasonographic,Imagings, Ultrasound,Medical Sonography,Ultrasonic Diagnoses,Ultrasonographic Imagings,Ultrasound, Diagnostic,Ultrasounds, Diagnostic
D014621 Vagina The genital canal in the female, extending from the UTERUS to the VULVA. (Stedman, 25th ed) Vaginas
D015984 Causality The relating of causes to the effects they produce. Causes are termed necessary when they must always precede an effect and sufficient when they initiate or produce an effect. Any of several factors may be associated with the potential disease causation or outcome, including predisposing factors, enabling factors, precipitating factors, reinforcing factors, and risk factors. Causation,Enabling Factors,Multifactorial Causality,Multiple Causation,Predisposing Factors,Reinforcing Factors,Causalities,Causalities, Multifactorial,Causality, Multifactorial,Causation, Multiple,Causations,Causations, Multiple,Enabling Factor,Factor, Enabling,Factor, Predisposing,Factor, Reinforcing,Factors, Enabling,Factors, Predisposing,Factors, Reinforcing,Multifactorial Causalities,Multiple Causations,Predisposing Factor,Reinforcing Factor
D017773 Pelvic Floor Soft tissue formed mainly by the pelvic diaphragm, which is composed of the two levator ani and two coccygeus muscles. The pelvic diaphragm lies just below the pelvic aperture (outlet) and separates the pelvic cavity from the PERINEUM. It extends between the PUBIC BONE anteriorly and the COCCYX posteriorly. Pelvic Diaphragm,Diaphragm, Pelvic,Diaphragms, Pelvic,Floor, Pelvic,Pelvic Diaphragms
D056887 Pelvic Organ Prolapse Abnormal descent of a pelvic organ resulting in the protrusion of the organ beyond its normal anatomical confines. Symptoms often include vaginal discomfort, DYSPAREUNIA; URINARY STRESS INCONTINENCE; and FECAL INCONTINENCE. Urogenital Prolapse,Vaginal Vault Prolapse,Organ Prolapse, Pelvic,Organ Prolapses, Pelvic,Pelvic Organ Prolapses,Prolapse, Pelvic Organ,Prolapse, Urogenital,Prolapse, Vaginal Vault,Prolapses, Pelvic Organ,Prolapses, Urogenital,Prolapses, Vaginal Vault,Urogenital Prolapses,Vaginal Vault Prolapses,Vault Prolapse, Vaginal,Vault Prolapses, Vaginal

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