Biomaterial Database

Diversity of the phosphoenolpyruvate/glucose phosphotransferase system in the Enterobacteriaceae. 1987

O M Bouvet, and P A Grimont

The presence of the phosphoenolpyruvate glucose phosphotransferase entry routes was studied in 97 genospecies of Enterobacteriaceae. Phosphoenolpyruvate(PEP)-dependent phosphorylation of alpha-methyl-D-glucoside and 2-deoxyglucose was evidenced in 72 species (group I organisms), suggesting the presence of both the IIGlc (formerly II-BGlc/IIIGlc) and IIMan (formerly II-B/II-AMan) entry routes. Erwinia amylovora, Budvicia aquatica and all species of Leminorella and Proteus (as defined by DNA relatedness studies) showed little or no PEP phosphorylation of 2-deoxyglucose, suggesting the absence of the IIMan entry route (group II organisms). Morganella morganii, Tatumella ptyseos and all species of Xenorhabdus and Providencia (as defined by DNA relatedness studies) showed little or no PEP phosphorylation of alpha-methyl-D-glucoside, suggesting the absence of the IIGlc entry route (group III organisms).

UI	MeSH Term	Description	Entries
D008358	Mannose	A hexose or fermentable monosaccharide and isomer of glucose from manna, the ash Fraxinus ornus and related plants. (From Grant & Hackh's Chemical Dictionary, 5th ed & Random House Unabridged Dictionary, 2d ed)	D-Mannose,Mannopyranose,Mannopyranoside,D Mannose
D010731	Phosphoenolpyruvate Sugar Phosphotransferase System	The bacterial sugar phosphotransferase system (PTS) that catalyzes the transfer of the phosphoryl group from phosphoenolpyruvate to its sugar substrates (the PTS sugars) concomitant with the translocation of these sugars across the bacterial membrane. The phosphorylation of a given sugar requires four proteins, two general proteins, Enzyme I and HPr and a pair of sugar-specific proteins designated as the Enzyme II complex. The PTS has also been implicated in the induction of synthesis of some catabolic enzyme systems required for the utilization of sugars that are not substrates of the PTS as well as the regulation of the activity of ADENYLYL CYCLASES. EC 2.7.1.-.	Phosphoenolpyruvate Hexose Phosphotransferases,Phosphoenolpyruvate-Glycose Phosphotransferase System,Hexose Phosphotransferases, Phosphoenolpyruvate,Phosphoenolpyruvate Glycose Phosphotransferase System,Phosphotransferase System, Phosphoenolpyruvate-Glycose,Phosphotransferases, Phosphoenolpyruvate Hexose,System, Phosphoenolpyruvate-Glycose Phosphotransferase
D010766	Phosphorylation	The introduction of a phosphoryl group into a compound through the formation of an ester bond between the compound and a phosphorus moiety.	Phosphorylations
D002463	Cell Membrane Permeability	A quality of cell membranes which permits the passage of solvents and solutes into and out of cells.	Permeability, Cell Membrane
D004755	Enterobacteriaceae	A family of gram-negative, facultatively anaerobic, rod-shaped bacteria that do not form endospores. Its organisms are distributed worldwide with some being saprophytes and others being plant and animal parasites. Many species are of considerable economic importance due to their pathogenic effects on agriculture and livestock.	Coliform Bacilli,Enterobacteria,Ewingella,Leclercia,Paracolobactrum,Sodalis
D005947	Glucose	A primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.	Dextrose,Anhydrous Dextrose,D-Glucose,Glucose Monohydrate,Glucose, (DL)-Isomer,Glucose, (alpha-D)-Isomer,Glucose, (beta-D)-Isomer,D Glucose,Dextrose, Anhydrous,Monohydrate, Glucose
D014050	Toluene	A widely used industrial solvent.