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Mammary carcinoma was induced in female Nb rats by implanting pellets of estrone at 25-28 days of age, and prostatic cancer was induced in male rats of the same strain by repeatedly implanting pellets of testosterone propionate. Feeding semipurified diets containing either 3% or 20% corn oil did not significantly affect the incidence or yield of mammary tumors, although tumors tended to appear somewhat earlier in animals on the high-fat diet, confirming the report of Dunning et al. published nearly 40 years ago. The yield of prostatic tumors was too low to draw any conclusions with respect to dietary fat. Hormonally induced mammary tumors appear to be less responsive to dietary fat than those induced by commonly used chemical carcinogens.
K K Carroll, and
R L Noble
April 1986,
Lipids,
K K Carroll, and
R L Noble
January 1985,
Princess Takamatsu symposia,
K K Carroll, and
R L Noble
February 1979,
Lipids,
K K Carroll, and
R L Noble
January 1981,
Cancer detection and prevention,
K K Carroll, and
R L Noble
March 1960,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
K K Carroll, and
R L Noble
January 1984,
Anticancer research,
K K Carroll, and
R L Noble
January 1968,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
K K Carroll, and
R L Noble
February 1958,
Acta physiologica Scandinavica,
K K Carroll, and
R L Noble
January 1980,
Progress in clinical and biological research,
K K Carroll, and
R L Noble
October 1980,
Biochimica et biophysica acta,
