Biomaterial Database

18 F-FDG and 68 Ga-FAPI-04 PET/CT Imaging of a Case With Immunoglobulin G4-Related Disease Presenting as Hepatic Masses. 2022

Zeyu Zhang, and Hui Jiang, and Lu Zhang, and Chao Cheng, and Changjing Zuo

From the Departments of Nuclear Medicine.

Two hepatic masses were discovered through ultrasonography in a 50-year-old man with increased CA19-9, which is highly suspicious for malignancy. PET/CT images revealed intense 18 F-FDG and 68 Ga-FAPI-04 uptake in intrahepatic lesions. Histopathology with biopsy confirmed the diagnosis of immunoglobulin G4 (IgG4)-related disease. Here, we reported a case of IgG4-related primary localized pseudotumor without any other organ involvement. We concluded that in clinical work, if intrahepatic masses show high uptake of 18 F-FDG or 68 Ga-FAPI-04, intrahepatic IgG4-related disease should be considered for differential diagnosis.

UI	MeSH Term	Description	Entries
D007074	Immunoglobulin G	The major immunoglobulin isotype class in normal human serum. There are several isotype subclasses of IgG, for example, IgG1, IgG2A, and IgG2B.	Gamma Globulin, 7S,IgG,IgG Antibody,Allerglobuline,IgG(T),IgG1,IgG2,IgG2A,IgG2B,IgG3,IgG4,Immunoglobulin GT,Polyglobin,7S Gamma Globulin,Antibody, IgG,GT, Immunoglobulin
D008297	Male		Males
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D005710	Gallium Radioisotopes	Unstable isotopes of gallium that decay or disintegrate emitting radiation. Ga atoms with atomic weights 63-68, 70 and 72-76 are radioactive gallium isotopes.	Radioisotopes, Gallium
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000072078	Positron Emission Tomography Computed Tomography	An imaging technique that combines a POSITRON-EMISSION TOMOGRAPHY (PET) scanner and a CT X RAY scanner. This establishes a precise anatomic localization in the same session.	CT PET,CT PET Scan,PET CT Scan,PET-CT,PET-CT Scan,Positron Emission Tomography-Computed Tomography,CT PET Scans,CT Scan, PET,CT Scans, PET,PET CT Scans,PET Scan, CT,PET Scans, CT,PET-CT Scans,Scan, CT PET,Scan, PET CT,Scan, PET-CT,Scans, CT PET,Scans, PET CT,Scans, PET-CT
D000077733	Immunoglobulin G4-Related Disease	A spectrum of systemic autoimmune diseases in which IMMUNOGLOBULIN G4 plays a pathophysiologic role. It can affect multiple organs in highly variable presentations, characterized by inflammatory lesions composed of IgG4-positive PLASMA CELLS, further infiltrated by T helper cells (T-LYMPHOCYTES, HELPER-INDUCER) when linked to progressive FIBROSIS and eventual organ damage.	IgG4-Related Kidney Disease,IgG4-Related Sclerosing Disease,Immunoglobulin G4-Related Kidney Disease,Immunoglobulin G4-Related Sclerosing Disease,IgG4 Related Systemic Disease,IgG4-Associated Autoimmune Disease,IgG4-RD,IgG4-Related Disease,Autoimmune Disease, IgG4-Associated,IgG4 Associated Autoimmune Disease,IgG4 Related Disease,IgG4 Related Kidney Disease,IgG4 Related Sclerosing Disease,IgG4-Associated Autoimmune Diseases,IgG4-Related Diseases,IgG4-Related Kidney Diseases,IgG4-Related Sclerosing Diseases,Immunoglobulin G4 Related Disease,Immunoglobulin G4 Related Kidney Disease,Immunoglobulin G4 Related Sclerosing Disease,Immunoglobulin G4-Related Diseases,Kidney Disease, IgG4-Related,Sclerosing Disease, IgG4-Related
D019788	Fluorodeoxyglucose F18	The compound is given by intravenous injection to do POSITRON-EMISSION TOMOGRAPHY for the assessment of cerebral and myocardial glucose metabolism in various physiological or pathological states including stroke and myocardial ischemia. It is also employed for the detection of malignant tumors including those of the brain, liver, and thyroid gland. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1162)	18F Fluorodeoxyglucose,18FDG,2-Fluoro-2-deoxy-D-glucose,2-Fluoro-2-deoxyglucose,Fludeoxyglucose F 18,18F-FDG,Fluorine-18-fluorodeoxyglucose,Fluorodeoxyglucose F 18,2 Fluoro 2 deoxy D glucose,2 Fluoro 2 deoxyglucose,F 18, Fludeoxyglucose,F 18, Fluorodeoxyglucose,F18, Fluorodeoxyglucose,Fluorine 18 fluorodeoxyglucose,Fluorodeoxyglucose, 18F