Biomaterial Database

Therapeutic use of contact lenses in alkali burns of the cornea. 1987

S J Bechara, and N Kara-José, and A H Pettinati

Rabbit eyes submitted to alkali burns (in 1 N NaOH, 7 mm, for 2 min) were evaluated as to the effect of contact lenses on the corneal reepithelialization. Forty eyes were used, divided into two groups: 3 weeks and those observed for 5 weeks. In each group, 10 eyes received a contact lens while 10 served as controls. From the daily evaluation of the corneal surface as well as the microscopic examinations at the end of the two periods of observation, we concluded that hydrophilic contact lenses provide a beneficial effect on alkali burns of the cornea, reducing the incidence of epithelial defects to statistically significant levels.

UI	MeSH Term	Description	Entries
D011817	Rabbits	A burrowing plant-eating mammal with hind limbs that are longer than its fore limbs. It belongs to the family Leporidae of the order Lagomorpha, and in contrast to hares, possesses 22 instead of 24 pairs of chromosomes.	Belgian Hare,New Zealand Rabbit,New Zealand Rabbits,New Zealand White Rabbit,Rabbit,Rabbit, Domestic,Chinchilla Rabbits,NZW Rabbits,New Zealand White Rabbits,Oryctolagus cuniculus,Chinchilla Rabbit,Domestic Rabbit,Domestic Rabbits,Hare, Belgian,NZW Rabbit,Rabbit, Chinchilla,Rabbit, NZW,Rabbit, New Zealand,Rabbits, Chinchilla,Rabbits, Domestic,Rabbits, NZW,Rabbits, New Zealand,Zealand Rabbit, New,Zealand Rabbits, New,cuniculus, Oryctolagus
D003263	Contact Lenses, Hydrophilic	Soft, supple contact lenses made of plastic polymers which interact readily with water molecules. Many types are available, including continuous and extended-wear versions, which are gas-permeable and easily sterilized.	Lenses, Contact, Hydrophilic,Soft Contact Lenses,Hydrophilic Contact Lens,Soft Contact Lens,Contact Lens, Hydrophilic,Contact Lens, Soft,Contact Lenses, Soft,Hydrophilic Contact Lenses,Lens, Hydrophilic Contact,Lens, Soft Contact,Lenses, Hydrophilic Contact,Lenses, Soft Contact
D003315	Cornea	The transparent anterior portion of the fibrous coat of the eye consisting of five layers: stratified squamous CORNEAL EPITHELIUM; BOWMAN MEMBRANE; CORNEAL STROMA; DESCEMET MEMBRANE; and mesenchymal CORNEAL ENDOTHELIUM. It serves as the first refracting medium of the eye. It is structurally continuous with the SCLERA, avascular, receiving its nourishment by permeation through spaces between the lamellae, and is innervated by the ophthalmic division of the TRIGEMINAL NERVE via the ciliary nerves and those of the surrounding conjunctiva which together form plexuses. (Cline et al., Dictionary of Visual Science, 4th ed)	Corneas
D005126	Eye Burns	Injury to any part of the eye by extreme heat, chemical agents, or ultraviolet radiation.	Burn, Eye,Burns, Eye,Eye Burn
D000468	Alkalies	Usually a hydroxide of lithium, sodium, potassium, rubidium or cesium, but also the carbonates of these metals, ammonia, and the amines. (Grant & Hackh's Chemical Dictionary, 5th ed)	Alkali,Alkalis
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D065306	Corneal Injuries	Damage or trauma inflicted to the CORNEA by external means.	Corneal Abrasions,Cornea Injuries,Corneal Damage,Corneal Scar,Corneal Trauma,Abrasion, Corneal,Cornea Injury,Corneal Abrasion,Corneal Damages,Corneal Injury,Corneal Scars,Corneal Traumas,Damage, Corneal,Injury, Cornea,Injury, Corneal,Scar, Corneal,Trauma, Corneal