Fall Prediction in People with Parkinson's Disease. 2022

Phuong Cao, and Cheol-Hong Min

A preliminary study result predicting fall events in patients with Parkinson's disease (PD) by using a simple motion sensor is described in this paper. Causes of falls in people with PD can be postural instability, freezing of gait, festinating gait, dyskinesias, visuospatial dysfunction, orthostatic hypotension, and posture problems. This study uses only one motion sensor in collecting data. Thus, only fall events caused by festinating gait factors, which are moments when the patient suddenly moves faster with smaller steps, can be performed and tested. In this preliminary study, fall event scenarios of simulated test cases are performed by five healthy young subjects aged 20 to 28 years old. The acceleration mode in the motion sensor provides information that can detect how fast the subjects move. Data collected by the sensor will be analyzed by simple analysis methods and machine learning techniques classification. The proposed study achieved an accuracy of 70.3% for the 10-class model, while for binary classification, the accuracy was 99%. Clinical Relevance-This study focuses on predicting falls by analyzing the gaits prior to an actual so that fall prediction can be possible. If falls can be predicted, researchers can develop other protective gear to prevent fall-related injuries not only for PD patients but also for the elderly.

UI MeSH Term Description Entries
D010300 Parkinson Disease A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75) Idiopathic Parkinson Disease,Lewy Body Parkinson Disease,Paralysis Agitans,Primary Parkinsonism,Idiopathic Parkinson's Disease,Lewy Body Parkinson's Disease,Parkinson Disease, Idiopathic,Parkinson's Disease,Parkinson's Disease, Idiopathic,Parkinson's Disease, Lewy Body,Parkinsonism, Primary
D005684 Gait Manner or style of walking. Gaits
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000058 Accidental Falls Falls due to slipping or tripping which may result in injury. Falls, Accidental,Falling,Falls,Slip and Fall,Accidental Fall,Fall and Slip,Fall, Accidental
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000368 Aged A person 65 years of age or older. For a person older than 79 years, AGED, 80 AND OVER is available. Elderly
D055815 Young Adult A person between 19 and 24 years of age. Adult, Young,Adults, Young,Young Adults
D020233 Gait Disorders, Neurologic Gait abnormalities that are a manifestation of nervous system dysfunction. These conditions may be caused by a wide variety of disorders which affect motor control, sensory feedback, and muscle strength including: CENTRAL NERVOUS SYSTEM DISEASES; PERIPHERAL NERVOUS SYSTEM DISEASES; NEUROMUSCULAR DISEASES; or MUSCULAR DISEASES. Ambulation Disorders, Neurologic,Charcot Gait,Charcot's Gait,Duck Gait,Gait Disorder, Sensorimotor,Gait Dysfunction, Neurologic,Gait, Athetotic,Gait, Broadened,Gait, Drop Foot,Gait, Festinating,Gait, Frontal,Gait, Hemiplegic,Gait, Hysterical,Gait, Reeling,Gait, Rigid,Gait, Scissors,Gait, Shuffling,Gait, Spastic,Gait, Stumbling,Gait, Unsteady,Gait, Widebased,Locomotion Disorders, Neurologic,Marche a Petit Pas,Neurologic Ambulation Disorders,Neurologic Locomotion Disorders,Rapid Fatigue of Gait,Sensorimotor Gait Disorder,Ambulation Disorder, Neurologic,Athetotic Gait,Broadened Gait,Charcot Gaits,Charcots Gait,Drop Foot Gait,Festinating Gait,Foot Gait, Drop,Frontal Gait,Gait Disorder, Neurologic,Gait Disorders, Sensorimotor,Gait Dysfunctions, Neurologic,Gait, Charcot,Gait, Charcot's,Gait, Duck,Gaits, Charcot,Hemiplegic Gait,Hysterical Gait,Locomotion Disorder, Neurologic,Neurologic Ambulation Disorder,Neurologic Gait Disorder,Neurologic Gait Disorders,Neurologic Gait Dysfunction,Neurologic Gait Dysfunctions,Neurologic Locomotion Disorder,Reeling Gait,Rigid Gait,Scissors Gait,Sensorimotor Gait Disorders,Shuffling Gait,Shuffling Gaits,Spastic Gait,Stumbling Gait,Unsteady Gait,Widebased Gait
D020820 Dyskinesias Abnormal involuntary movements which primarily affect the extremities, trunk, or jaw that occur as a manifestation of an underlying disease process. Conditions which feature recurrent or persistent episodes of dyskinesia as a primary manifestation of disease may be referred to as dyskinesia syndromes (see MOVEMENT DISORDERS). Dyskinesias are also a relatively common manifestation of BASAL GANGLIA DISEASES. Asterixis,Ballismus,Hemiballismus,Involuntary Movements,Lingual-Facial-Buccal Dyskinesia,Orofacial Dyskinesia,Abnormal Movements,Hemiballism,Linguofacial Dyskinesia,Oral Dyskinesia,Oral-Facial Dyskinesia,Tardive Oral Dyskinesia,Abnormal Movement,Dyskinesia,Dyskinesia, Lingual-Facial-Buccal,Dyskinesia, Linguofacial,Dyskinesia, Oral,Dyskinesia, Oral-Facial,Dyskinesia, Orofacial,Dyskinesias, Lingual-Facial-Buccal,Dyskinesias, Linguofacial,Dyskinesias, Oral,Dyskinesias, Oral-Facial,Dyskinesias, Orofacial,Involuntary Movement,Lingual Facial Buccal Dyskinesia,Lingual-Facial-Buccal Dyskinesias,Linguofacial Dyskinesias,Movement, Abnormal,Movement, Involuntary,Movements, Abnormal,Movements, Involuntary,Oral Dyskinesias,Oral Facial Dyskinesia,Oral-Facial Dyskinesias,Orofacial Dyskinesias,Tardive Oral Dyskinesias

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