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In this study, the influence of 4 after-work emollients on the healing of irritant skin reactions of varying intensity was assessed. To this end 5 patch tests with sodium lauryl sulphate (SLS) 2.5 g/v% were performed on the volar side of the forearm of 30 healthy Caucasian volunteers. Patch tests were removed after 12 h (group A, n = 10), 24 h (group B, n = 10) or 48 h (group C, n = 10). Then standard amounts of the emollients were applicated to the induced skin reactions, twice daily for a period of 5 days. One skin site served as a control. Skin sites were evaluated before, during and after the test period using laser Doppler flow measurements, skin vapor loss measurements and a visual scoring system. In all groups, data obtained from the skin sites treated with the emollients did not differ significantly from the data obtained from the control site. Thus, skin regeneration of the irritant skin reactions was not really enhanced by the application of these preparations. Further investigations on after-work emollient creams with physiologically better adapted constituents are necessary.
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
January 1995,
Current problems in dermatology,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
February 1991,
Contact dermatitis,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
January 2005,
Acta dermato-venereologica,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
May 1995,
Contact dermatitis,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
May 1957,
Journal of the American Medical Association,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
January 1982,
Urological research,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
September 1957,
The Journal of investigative dermatology,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
March 1964,
The British journal of dermatology,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
August 2007,
The Journal of allergy and clinical immunology,
R Blanken, and
P G van der Valk, and
J P Nater, and
H Dijkstra
February 2005,
Postgraduate medical journal,
