A Case of Pancreatic Neuroendocrine Tumor G3 Which Responded Remarkably to Chemotherapy. 2022

Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
Third Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan.

Pancreatic neuroendocrine carcinoma (NEC) as classified in the World Health Organization (WHO) 2010 was reclassified in the WHO 2017 as either neuroendocrine tumor (NET) G3 or NEC. An accurate diagnosis based on the WHO 2017 classification is important in order treating this disease appropriately. We report a case diagnosed as NET G3 that responded remarkably well to treatment with streptozocin. The patient would likely not have received the streptozocin treatment if she had been diagnosed with NEC. The WHO 2017 classification is reasonable for the treatment of advanced pancreatic neuroendocrine neoplasms.

UI MeSH Term Description Entries
D010190 Pancreatic Neoplasms Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA). Cancer of Pancreas,Pancreatic Cancer,Cancer of the Pancreas,Neoplasms, Pancreatic,Pancreas Cancer,Pancreas Neoplasms,Pancreatic Acinar Carcinoma,Pancreatic Carcinoma,Acinar Carcinoma, Pancreatic,Acinar Carcinomas, Pancreatic,Cancer, Pancreas,Cancer, Pancreatic,Cancers, Pancreas,Cancers, Pancreatic,Carcinoma, Pancreatic,Carcinoma, Pancreatic Acinar,Carcinomas, Pancreatic,Carcinomas, Pancreatic Acinar,Neoplasm, Pancreas,Neoplasm, Pancreatic,Neoplasms, Pancreas,Pancreas Cancers,Pancreas Neoplasm,Pancreatic Acinar Carcinomas,Pancreatic Cancers,Pancreatic Carcinomas,Pancreatic Neoplasm
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013311 Streptozocin An antibiotic that is produced by Stretomyces achromogenes. It is used as an antineoplastic agent and to induce diabetes in experimental animals. Streptozotocin,2-Deoxy-2-((methylnitrosoamino)carbonyl)amino-D-glucose,Streptozotocine,Zanosar
D060787 Neoplasm Grading Methods which attempt to express in replicable terms the level of CELL DIFFERENTIATION in neoplasms as increasing ANAPLASIA correlates with the aggressiveness of the neoplasm. Gleason Grading,Gleason Score,Tumor Grading,Grading, Gleason,Grading, Neoplasm,Grading, Tumor,Score, Gleason
D018358 Neuroendocrine Tumors Tumors whose cells possess secretory granules and originate from the neuroectoderm, i.e., the cells of the ectoblast or epiblast that program the neuroendocrine system. Common properties across most neuroendocrine tumors include ectopic hormone production (often via APUD CELLS), the presence of tumor-associated antigens, and isozyme composition. Neuroendocrine Tumor,Tumor, Neuroendocrine,Tumors, Neuroendocrine

Related Publications

Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
March 1987, Japanese journal of clinical oncology,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
November 2000, Gan to kagaku ryoho. Cancer & chemotherapy,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
December 2015, Clinical journal of gastroenterology,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
November 1998, Gan to kagaku ryoho. Cancer & chemotherapy,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
May 2019, Annals of surgical oncology,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
September 1990, Gan no rinsho. Japan journal of cancer clinics,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
March 2015, Frontiers of medicine,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
March 1984, Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
January 2017, Case reports in oncology,
Satoru Nebuya, and Shinji Oe, and Yoshikazu Harada, and Yusuke Takeuchi, and Akitoshi Yoneda, and Yudai Koya, and Koichiro Miyagawa, and Yuichi Honma, and Michihiko Shibata, and Masaru Harada
March 2017, Pancreas,
Copied contents to your clipboard!