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Impact of Mechanical Circulatory Support on Exercise Capacity in Patients With Advanced Heart Failure. 2022
Janice Huang, and
Barry J McDonnell, and
Justin S Lawley, and
Jessica Byrd, and
Eric J Stöhr, and
William K Cornwell
Department of Medicine-Cardiology, University of Colorado Anschutz Medical Campus, Aurora, CO.
Approximately 6 million individuals have heart failure in the United States alone and 15 million in Europe. Left ventricular assist devices (LVAD) improve survival in these patients, but functional capacity may not fully improve. This article examines the hypothesis that patients supported by LVAD experience persistent reductions in functional capacity and explores mechanisms accounting for abnormalities in exercise tolerance.
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