Ultrasound (sonication) treatment can be used directly for dehydration or pre-treatment before the osmotic dehydration (OD) procedure of fruit or vegetable particles. The combination of this technique with the OD technique can further improve the dehydration process efficiencies by increasing the mass transfer rates and enhancing final product quality. In this study, apple slices were osmotically dehydrated in different hypertonic sucrose solutions and assisted with or without ultrasound. Sucrose concentrations (in three levels of 30, 40, and 50° Brix), sonication power (in three levels of 0, 75, and 150 W), and treatment time (in six time intervals: 10, 20, 30, 40, 50, and 60 min) were the factors investigated concerning weight reduction, soluble solids gain, water loss and rehydration. Also, mass transfer kinetics were modelled according to Page, Newton, Midilli, Logarithmic, Verma, and Two terms equations. Increased sucrose solution concentration resulted in higher weight reduction, soluble solids gain and water loss. Also, increased sonication power levels resulted in higher weight reduction, soluble solids gain and water loss. The average rehydration ratio of apple slices decreased from 237.7 to 177.5%, by increasing osmotic solution concentration from 30 to 50%. The Page equation showed the best fitting for water loss data. The effective moisture diffusivity (Deff) of apple slices during OD calculated using Fick's second law applied to a slab geometry was found to be in the range of 1.48 × 10-10 and 4.62 × 10-10 m2s-1 for water loss.