14 children with anorectal prolapse have been treated by injection therapy with 25% saline solution. Experimental studies have shown no noticeable reactions between rectum and surrounding area, as far as adhesion and thus rectal fixation are concerned. Manometric examinations show an increased contraction tendency of the Musculus puborectalis after injection, which should lead to a depression of the kink at the rectosigmoidal junction and to a healing of the prolapse. The associated stool-regulating measures contribute a lot to remedy the prolapsed rectum.