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With a purified beta-propiolactone-inactivated rabies virus, a significant increase in footpad swelling was elicited in normal or in BCG-pretreated mice after immunization with varying doses of rabies vaccine. These footpad reactions were shown to peak at 24 h and to be associated with an infiltration of newly formed blood monocytes demonstrated by histology and [125I]deoxyuridine labeling. A relationship between the lymphoproliferation and the degree of sensitization is described, and the susceptibility to cyclophosphamide treatment is also examined. Adoptive transfer of specific reactivity to normal recipient mice with immune lymphoid cells, but not with immune serum, was demonstrated, and the results represent another argument for a cell-mediated immunological mechanism.
P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
January 1976,
The Journal of infectious diseases,
P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
November 1976,
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P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
January 1980,
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P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
December 1965,
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P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
September 1968,
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P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
February 1971,
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P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
January 1983,
Microbiology and immunology,
P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
March 1978,
Immunology,
P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
November 1984,
Cellular immunology,
P H Lagrange, and
H Tsiang, and
B Hurtrel, and
P Ravisse
November 1975,
Journal of the National Cancer Institute,
